{"id":3635,"date":"2014-12-04T18:52:20","date_gmt":"2014-12-04T18:52:20","guid":{"rendered":"https:\/\/lpfch.org\/foundation-grants-bear-necessities-helps-advance-diagnosis-and-treatment-of-childhood-cancer\/"},"modified":"2024-02-14T14:06:56","modified_gmt":"2024-02-14T14:06:56","slug":"foundation-grants-bear-necessities-helps-advance-diagnosis-and-treatment-of-childhood-cancer","status":"publish","type":"post","link":"https:\/\/lpfch.org\/es\/impact-stories\/foundation-grants-bear-necessities-helps-advance-diagnosis-and-treatment-of-childhood-cancer\/","title":{"rendered":"Subvenciones de la Fundaci\u00f3n: Bear Necessities ayuda a mejorar el diagn\u00f3stico y el tratamiento del c\u00e1ncer infantil."},"content":{"rendered":"<p>Este verano, cuatro investigadores de la Facultad de Medicina de la Universidad de Stanford recibieron un total de $160.000 de la Bear Necessities Pediatric Cancer Foundation por sus esfuerzos para avanzar en el diagn\u00f3stico y tratamiento de los c\u00e1nceres infantiles.<\/p>\n<p>Las subvenciones de $40.000 cada una apoyar\u00e1n los siguientes proyectos:<\/p>\n<p><strong>Dr. Alejandro Sweet-Cordero,<\/strong>      Profesor asociado de pediatr\u00eda, recibi\u00f3 apoyo por sus esfuerzos para comprender mejor un tipo raro de c\u00e1ncer pedi\u00e1trico llamado sarcoma de Ewing. El sarcoma de Ewing es causado por un tipo de cambio gen\u00e9tico llamado translocaci\u00f3n. Esta translocaci\u00f3n resulta en la producci\u00f3n de una nueva prote\u00edna llamada EWS\/FLI-1.<\/p>\n<p>La investigaci\u00f3n de      <strong>Bryan Mitton, MD, PhD,<\/strong> Instructor cl\u00ednico en pediatr\u00eda, se centra en la leucemia mieloide aguda (LMA), un c\u00e1ncer de r\u00e1pido crecimiento y dif\u00edcil de tratar que se origina en la m\u00e9dula \u00f3sea. Mitton busca comprender la se\u00f1alizaci\u00f3n aberrante (el sistema de comunicaci\u00f3n que regula las actividades celulares b\u00e1sicas) que caracteriza a la LMA de alto riesgo.<\/p>\n<p><strong>Marius Wernig, MD, PhD,<\/strong>      El profesor adjunto de patolog\u00eda utilizar\u00e1 los fondos para investigar m\u00e1s a fondo un c\u00e1ncer cerebral mortal llamado glioma. Los tratamientos existentes para los gliomas, o c\u00e1nceres de las c\u00e9lulas progenitoras gliales del cerebro, no son muy eficaces y pueden tener efectos secundarios adversos, especialmente en ni\u00f1os. Wernig y sus colegas intentar\u00e1n identificar los cambios moleculares clave que convierten las c\u00e9lulas progenitoras gliales normales en cancerosas y actuar sobre ellos, con el objetivo de desarrollar terapias m\u00e1s eficaces y con menos efectos secundarios.<\/p>\n<p><strong>Dra. Viola Caretti, PhD,<\/strong> La investigadora postdoctoral recibi\u00f3 el premio por su labor en la investigaci\u00f3n de los gliomas de alto grado (HGG), la principal causa de muerte infantil relacionada con tumores cerebrales. Caretti planea estudiar el papel de las descargas neuronales en el crecimiento de las c\u00e9lulas HGG. En \u00faltima instancia, busca comprender mejor la interacci\u00f3n entre las neuronas y el crecimiento de las c\u00e9lulas tumorales para poder abordar esta interacci\u00f3n y desarrollar nuevos tratamientos para los HGG.<\/p>\n<p>\u201cNos enorgullece apoyar a investigadores de todo el pa\u00eds que est\u00e1n logrando avances significativos en la b\u00fasqueda de una cura y terapias para el c\u00e1ncer pedi\u00e1trico\u201d, afirm\u00f3 Susan Mura, directora financiera de la Fundaci\u00f3n Bear Necessities para el C\u00e1ncer Pedi\u00e1trico. \u201cEl trabajo que realizan los investigadores de la Universidad de Stanford es fundamental para ayudarnos a cumplir nuestra misi\u00f3n de eliminar el c\u00e1ncer pedi\u00e1trico y brindar esperanza y apoyo a quienes lo padecen\u201d.<\/p>\n<p>La Fundaci\u00f3n contra el C\u00e1ncer Pedi\u00e1trico Bear Necessities, con sede en Chicago, cuya misi\u00f3n es eliminar el c\u00e1ncer pedi\u00e1trico y brindar esperanza y apoyo a quienes lo padecen, ha otorgado seis subvenciones a investigadores de Stanford desde 2007.<\/p>","protected":false},"excerpt":{"rendered":"<p>Cuatro investigadores de la Facultad de Medicina de la Universidad de Stanford recibieron este verano un total de $160,000 de la Bear Necessities Pediatric Cancer Foundation por su\u2026<\/p>","protected":false},"author":17,"featured_media":10479,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"categories":[148],"class_list":["post-3635","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-in-the-news","health_topic-pediatric-cancer"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.2 (Yoast SEO v27.2) - 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