{"id":3526,"date":"2014-08-20T23:27:52","date_gmt":"2014-08-20T23:27:52","guid":{"rendered":"https:\/\/lpfch.org\/expanding-the-realm-of-possibility-10-breakthroughs-in-pediatric-organ-transplantation-pioneered-at-lucile-packard-childrens-hospital\/"},"modified":"2024-09-13T18:27:35","modified_gmt":"2024-09-13T18:27:35","slug":"expanding-the-realm-of-possibility-10-breakthroughs-in-pediatric-organ-transplantation-pioneered-at-lucile-packard-childrens-hospital","status":"publish","type":"post","link":"https:\/\/lpfch.org\/ko\/impact-stories\/expanding-the-realm-of-possibility-10-breakthroughs-in-pediatric-organ-transplantation-pioneered-at-lucile-packard-childrens-hospital\/","title":{"rendered":"\uac00\ub2a5\uc131\uc758 \uc601\uc5ed \ud655\uc7a5: \ub8e8\uc2e4 \ud328\ucee4\ub4dc \uc5b4\ub9b0\uc774 \ubcd1\uc6d0\uc5d0\uc11c \uac1c\ucc99\ud55c \uc18c\uc544 \uc7a5\uae30 \uc774\uc2dd \ubd84\uc57c\uc758 10\uac00\uc9c0 \ud68d\uae30\uc801\uc778 \uc131\uacfc"},"content":{"rendered":"<p><span style=\"font-weight: bold; font-size: 1.231em; line-height: 1.538em;\">1. \ub300\uaddc\ubaa8 \uc870\uc9c1<\/span><span style=\"font-weight: bold; font-size: 1.231em; line-height: 1.538em;\">\uc5b4\ub9b0\uc544\uc774\ub4e4\uc744 \uc704\ud55c \ub2f5\ubcc0<\/span><\/p>\n<p>&quot;\uc5b4\ub9b0\uc774 \uc7a5\uae30\uac00 \ub9cc\uc131\uc801\uc73c\ub85c \ubd80\uc871\ud558\uae30 \ub54c\ubb38\uc5d0 \ucc3d\uc758\uc801\uc778 \uc811\uadfc\uc774 \ud544\uc694\ud588\uc2b5\ub2c8\ub2e4.&quot;\ub77c\uace0 \uce74\ub97c\ub85c\uc2a4 \uc5d0\uc2a4\ud0a4\ubca8(Carlos Esquivel, MD, PhD) \ubc15\uc0ac\ub294 \ub9d0\ud569\ub2c8\ub2e4. \uadf8\ub294 \uc0ac\ub9dd\ud55c \uc131\uc778 \uae30\uc99d\uc790\uc758 \uac04\uc744 \ub450 \uac1c\uc758 \uc0dd\uc874 \uac00\ub2a5\ud55c \ubd80\ubd84\uc73c\ub85c \ub098\ub204\uc5b4 \ub450 \ud658\uc790(\uc5b4\ub9b0\uc774 \ud55c \uba85\uacfc \uc131\uc778 \ud55c \uba85)\uc5d0\uac8c \uc774\uc2dd\ud558\ub294 \ucd5c\ucd08\uc758 \uc678\uacfc\uc758 \uc911 \ud55c \uba85\uc785\ub2c8\ub2e4.<\/p>\n<p>\uc5d0\uc2a4\ud0a4\ubca8\uacfc \uadf8\uc758 \ub3d9\ub8cc\ub4e4\uc740 \uc0b4\uc544\uc788\ub294 \uc131\uc778 \uae30\uc99d\uc790\uc758 \uac04 \uc77c\ubd80\ub97c \uc5b4\ub9b0\uc774\uc5d0\uac8c \uc131\uacf5\uc801\uc73c\ub85c \uc774\uc2dd\ud558\ub294 \ub370 \ucd5c\ucd08\ub85c \uc131\uacf5\ud55c \uc5f0\uad6c\uc790\ub4e4 \uc911 \ud55c \uba85\uc774\uc5c8\uc2b5\ub2c8\ub2e4. \ub180\ub78d\uac8c\ub3c4, \uc774\uc2dd\ub41c \uac04\uc740 \uc5b4\ub9b0\uc774\uac00 \uc131\uc7a5\ud568\uc5d0 \ub530\ub77c \uc815\uc0c1 \ud06c\uae30\ub85c \uc790\ub77c\uba70, \uc131\uc778 \uae30\uc99d\uc790\uc758 \uac04 \ub610\ud55c \uc6d0\ub798 \ud06c\uae30\ub85c \ud68c\ubcf5\ub429\ub2c8\ub2e4.<\/p>\n<h2>2. \ubd80\ubaa8\uc5d0\uc11c \uc790\uc2dd\uc73c\ub85c<\/h2>\n<p>\ubd80\ubaa8 \uae30\uc99d\uc790\ub294 \uc790\ub140\uc5d0\uac8c \uc5b4\ub290 \uc815\ub3c4 \uba74\uc5ed\uc744 \ubb3c\ub824\uc904 \uc218 \uc788\uae30 \ub54c\ubb38\uc5d0, 2\uc138 \ubbf8\ub9cc\uc758 \uc2e0\uc7a5 \uc774\uc2dd \ud658\uc790\ub294 \uc885\uc885 \uc5b4\uba38\ub2c8\ub098 \uc544\ubc84\uc9c0\ub85c\ubd80\ud130 \uc0c8\ub85c\uc6b4 \uc7a5\uae30\ub97c \uc774\uc2dd\ubc1b\uc2b5\ub2c8\ub2e4. \ud328\ucee4\ub4dc \uc5b4\ub9b0\uc774\ubcd1\uc6d0\uc5d0\uc11c\ub294 \ubd80\ubaa8-\uc790\ub140 \uac04 \uc2e0\uc7a5 \uc774\uc2dd\uc758 \ud3c9\uade0 \uc218\uba85\uc774 20\ub144 \uc774\uc0c1\uc785\ub2c8\ub2e4. \uac70\ubd80 \ubc18\uc751 \uae30\uc804\uc5d0 \ub300\ud55c \uc774\ud574\uac00 \ub192\uc544\uc9c0\uace0 \ub354 \ub098\uc740 \uba74\uc5ed \uc5b5\uc81c \uc804\ub7b5\uc774 \uac1c\ubc1c\ub428\uc5d0 \ub530\ub77c \uc2e0\uc7a5 \uc0dd\uc874\uc728\uc774 \uc99d\uac00\ud560 \uac83\uc73c\ub85c \uc608\uc0c1\ub429\ub2c8\ub2e4.<\/p>\n<h2>3. \uc77c\uce58 \ubd88\ud544\uc694<\/h2>\n<p>30\ub144 \uc804\ub9cc \ud574\ub3c4 \ud608\uc561\ud615\uc774 \uc77c\uce58\ud558\uc9c0 \uc54a\ub294 \uae30\uc99d\uc790\uc758 \uac04\uc744 \uc774\uc2dd\ud558\ub294 \uc18c\uc544\ubcd1\uc6d0\uc740 \uac70\uc758 \uc5c6\uc5c8\uc2b5\ub2c8\ub2e4. \uc624\ub298\ub0a0 \ud328\ucee4\ub4dc \uc5b4\ub9b0\uc774\ubcd1\uc6d0 \uc758\ub8cc\uc9c4\uc740 \uc5b4\ub9b0 \ud658\uc790\uc5d0\uac8c\ub3c4 \ud608\uc561\ud615\uc774 \uc77c\uce58\ud558\uc9c0 \uc54a\ub294 \uac04 \uc774\uc2dd\uc744 \uc815\uae30\uc801\uc73c\ub85c \uc2dc\ud589\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. \ud608\uc561\ud615 \uad50\ucc28 \uc774\uc2dd\uc740 \uc544\uc774\ub4e4\uc774 \uc774\uc2dd\uc744 \uae30\ub2e4\ub9ac\ub294 \uc2dc\uac04\uc744 \ub2e8\ucd95\uc2dc\ucf1c \uc90d\ub2c8\ub2e4.<\/p>\n<h2>4. \uac00\uc7a5 \uc791\uc740 \ud658\uc790<\/h2>\n<p>\uc5b4\ub9b0\uc544\uc774\uc758 \uacbd\uc6b0, \uac04\uacfc \uc2e0\uc7a5 \uc774\uc2dd\uc5d0 \uad00\uc5ec\ud558\ub294 \ud608\uad00\uc774 \ub9e4\uc6b0 \uc791\uc544 \uc678\uacfc\uc758\ub294 \uc721\uc548\uc73c\ub85c\ub294 \ubcfc \uc218 \uc5c6\ub294 \ubd09\ud569\uc0ac\ub97c \uc0ac\uc6a9\ud574\uc57c \ud569\ub2c8\ub2e4. \uc131\uc778 \uc2e0\uc7a5\uc744 \uc774\uc2dd\ubc1b\ub294 \uc5b4\ub9b0 \ud658\uc790\ub4e4\uc744 \uc704\ud574, \ud328\ucee4\ub4dc \uc5b4\ub9b0\uc774\ubcd1\uc6d0 \uc758\ub8cc\uc9c4\uc740 \ud608\ub958\ub7c9\uc744 \uc99d\uac00\uc2dc\ud0a4\uae30 \uc704\ud574 \uacf5\uaca9\uc801\uc778 \uc218\uc561 \ubcf4\ucda9 \uae30\ubc95\uc744 \uac1c\ucc99\ud588\uc2b5\ub2c8\ub2e4. \uc774\uc2dd\ud300\uc740 \uc644\ubcbd\ud55c \uc218\uc220 \uc815\ubc00\ub3c4 \uc678\uc5d0\ub3c4 \uc774\uc2dd \uc804\ud6c4\uc5d0 \uc18c\uc544\uc5d0\uac8c \uc885\ud569\uc801\uc778 \uad00\ub9ac\ub97c \uc81c\uacf5\ud558\uc5ec \ucd5c\uc0c1\uc758 \uacb0\uacfc\ub97c \ubcf4\uc7a5\ud569\ub2c8\ub2e4. \ud604\uc7ac \ud328\ucee4\ub4dc \uc5b4\ub9b0\uc774\ubcd1\uc6d0\uc5d0\uc11c\ub294 2\uc138 \ubbf8\ub9cc \uac04 \uc774\uc2dd \ud658\uc790\uc758 \uc0dd\uc874\uc728\uc774 \uac70\uc758 100%\uc5d0 \ub2ec\ud558\uba70, \uc2e0\uc0dd\uc544\ub3c4 \uc774\uc2dd \uc218\uc220\uc744 \ud1b5\ud574 \uc0dd\uba85\uc744 \uad6c\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<h2>5. \u201c\uc774\uc2dd \ubd88\uac00\ub2a5\ud55c\u201d \uc544\uc774\ub4e4<\/h2>\n<p>\uc2e0\uc7a5 \uc774\uc2dd\uc774 \ud544\uc694\ud55c \ub9ce\uc740 \uc544\uc774\ub4e4\uc740 \uc774\uc804 \uc774\uc2dd, \uc218\ud608 \ub610\ub294 \uc608\ubc29 \uc811\uc885\uc73c\ub85c \uc778\ud574 \uc0c8\ub85c\uc6b4 \uc7a5\uae30\ub97c \uacf5\uaca9\ud560 \uc218 \uc788\ub294 \uace0\ub3c4\ub85c \ubbfc\uac10\ud55c \uba74\uc5ed \uccb4\uacc4\ub97c \uac16\uac8c \ub429\ub2c8\ub2e4. \ud328\ucee4\ub4dc \uc5b4\ub9b0\uc774 \ubcd1\uc6d0\uc740 &quot;\uc774\uc2dd \ubd88\uac00&quot;\ub85c \uac04\uc8fc\ub418\ub294 \uc544\uc774\ub4e4\uc744 \uc704\ud55c \uce58\ub8cc\ub97c \uc81c\uacf5\ud558\ub294 \uba87 \uc548 \ub418\ub294 \ubcd1\uc6d0 \uc911 \ud558\ub098\uc785\ub2c8\ub2e4. \ud608\uc7a5\uad50\ud658\uc220\uc774\ub77c\ub294 \uce58\ub8cc\ubc95\uc740 \ub2e4\ub978 \ud608\uc561\ud615\uc744 \uac00\uc9c4 \uae30\uc99d\uc790\uc758 \uc2e0\uc7a5\uc744 \uacf5\uaca9\ud560 \uac00\ub2a5\uc131\uc774 \uc788\ub294 \ud56d\uccb4\ub97c \uc81c\uac70\ud558\ub294 \uac83\uc785\ub2c8\ub2e4. \uc2a4\ud0e0\ud37c\ub4dc\uc5d0\uc11c \uac1c\ubc1c\ub41c \uac80\uc0ac\uc2e4 \uac80\uc0ac\ub97c \ud1b5\ud574 \uc815\ub9e5 \uba74\uc5ed\uae00\ub85c\ubd88\ub9b0 \uc8fc\uc785\uc73c\ub85c \uc81c\uac70\ud560 \uc218 \uc788\ub294 \ud2b9\uc815 \ud56d\uccb4\uac00 \ud658\uc790\uc5d0\uac8c \uc788\ub294\uc9c0\ub3c4 \ud655\uc778\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<h2>6. \ub2e4\ubc1c\uc131 \uc7a5\uae30 \uc774\uc2dd<\/h2>\n<p>\ud328\ucee4\ub4dc \uc5b4\ub9b0\uc774\ubcd1\uc6d0\uc740 \uac04-\uc2e0\uc7a5, \uac04-\uc2ec\uc7a5, \uac04-\uc7a5, \uadf8\ub9ac\uace0 \ucd5c\ucd08\uc758 \uc18c\uc544 \uac04-\uc774\uc911 \ud3d0 \uc774\uc2dd\uc744 \ud3ec\ud568\ud55c \ub2e4\uc7a5\uae30 \uc774\uc2dd\uc744 \uc2dc\ud589\ud558\ub294 \uba87 \uc548 \ub418\ub294 \uc18c\uc544\ubcd1\uc6d0 \uc911 \ud558\ub098\uc785\ub2c8\ub2e4. \uc5d0\uc2a4\ud0a4\ubca8\uc740 &quot;\uc774 \ubcd1\uc6d0\uc5d0\uc11c \uce58\ub8cc\ubc1b\ub294 \ud55c \uac00\uc9c0 \uc7a5\uc810\uc740 \ub9ce\uc740 \uc774\uc2dd \uc804\ubb38\uc758\uac00 \ubcd1\uc6d0\uc5d0 \uc0c1\uc8fc\ud558\uace0 \uc788\ub2e4\ub294 \uac83\uc785\ub2c8\ub2e4.&quot;\ub77c\uace0 \ub9d0\ud569\ub2c8\ub2e4.<\/p>\n<h2>7. \uc774\uc2dd\uc758 \ub300\uc548<\/h2>\n<p>\uc18c\uc544 \uc704\uc7a5\ubcd1\ud559 \uad50\uc218\uc778 \ucf00\ub124\uc2a4 \ucf55\uc2a4(Kenneth Cox) \ubc15\uc0ac\uc640 \ub2e4\ub978 \uc5f0\uad6c\uc790\ub4e4\uc740 \uc77c\ubd80 \uac04 \uc774\uc2dd\uc758 \ud544\uc694\uc131\uc744 \uc608\ubc29\ud558\ub294 \ud601\uc2e0\uc801\uc778 \uce58\ub8cc\ubc95\uc744 \uac1c\ubc1c\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. 1993\ub144, \ucf55\uc2a4 \ubc15\uc0ac\ub294 \ubc18\ucf54\ub9c8\uc774\uc2e0\uc774\ub77c\ub294 \ud56d\uc0dd\uc81c\uac00 \uc138\uade0 \uac10\uc5fc\ubfd0\ub9cc \uc544\ub2c8\ub77c \uc6d0\ubc1c\uc131 \uacbd\ud654\uc131 \ub2f4\uad00\uc5fc\uc774\ub77c\ub294 \ud76c\uadc0 \uac04 \ubc0f \ub300\uc7a5 \uc9c8\ud658 \uce58\ub8cc\uc5d0\ub3c4 \ub3c4\uc6c0\uc774 \ub41c\ub2e4\ub294 \uac83\uc744 \ubc1c\uacac\ud588\uc2b5\ub2c8\ub2e4. \uc774\uc804\uc5d0\ub294 \uc774\uc2dd\uc774 \uc774 \uc9c8\ubcd1\uc744 \uce58\ub8cc\ud558\ub294 \uc720\uc77c\ud55c \ubc29\ubc95\uc774\uc5c8\uc2b5\ub2c8\ub2e4. \ub610\ud55c, \ubc15\uc0ac\ud6c4 \uc5f0\uad6c\uc6d0\uc778 \ub808\ubca0\uce74 \ubc84\ud034\uc2a4\ud2b8 \ub9e5\ucf04\uc9c0(Rebecca Berquist McKenzie) \ubc15\uc0ac\ub294 \uae09\uc131 \uac04\uc5fc\uc73c\ub85c \uc778\ud55c \uac04\ubd80\uc804 \uc18c\uc544 \uce58\ub8cc\ub97c \uc704\ud55c \uc0c8\ub85c\uc6b4 \ud504\ub85c\ud1a0\ucf5c\uc744 \uac1c\ubc1c\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. \ud604\uc7ac\uae4c\uc9c0 \uba74\uc5ed \ub9e4\uac1c \uac04\uc5fc\uc744 \uc553\uace0 \uc788\ub294 9\uba85\uc758 \uc18c\uc544\uac00 \uce58\ub8cc\ub97c \ubc1b\uc558\uc73c\uba70, \ud604\uc7ac \uc808\ubc18 \uc774\uc0c1\uc774 \uac04\uc5fc\uc774 \uc5c6\uace0 \uac04 \uae30\ub2a5\uc774 \uc815\uc0c1\ud654\ub418\uc5b4 \uc774\uc2dd\uc774 \ud544\uc694\ud558\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4.<\/p>\n<h2>8. \uc2a4\ud14c\ub85c\uc774\ub4dc\ub294 \uc774\uc81c \uadf8\ub9cc<\/h2>\n<p>\uc218\uc2ed \ub144 \ub3d9\uc548 \uc2e0\uc7a5 \uc774\uc2dd\uc744 \ubc1b\uc740 \uc18c\uc544\ub4e4\uc740 \uc7a5\uae30 \uac70\ubd80 \ubc18\uc751\uc744 \uc608\ubc29\ud558\uae30 \uc704\ud574 \uc2a4\ud14c\ub85c\uc774\ub4dc\ub97c \ud22c\uc5ec\ubc1b\uc558\uc2b5\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \uc2a4\ud14c\ub85c\uc774\ub4dc\uc758 \ub9cc\uc131 \uc0ac\uc6a9\uc740 \uace0\uad00\uc808 \uc774\ud615\uc131\uc99d, \uad00\uc808\uc5fc, \ub2f9\ub1e8\ubcd1, \uac10\uc5fc, \uadf8\ub9ac\uace0 \ub2e4\uc591\ud55c \ub300\uc0ac \uc9c8\ud658\uacfc \uac19\uc740 \uc2ec\uac01\ud55c \ud569\ubcd1\uc99d\uc744 \uc720\ubc1c\ud558\ub294 \uacbd\uc6b0\uac00 \ub9ce\uc558\uc2b5\ub2c8\ub2e4. 1990\ub144\ub300, \ud328\ucee4\ub4dc \uc5b4\ub9b0\uc774 \ubcd1\uc6d0 \uc758\uc0ac\ub4e4\uc740 \uc774\uc2dd \ud6c4 \ud658\uc790\ub4e4\uc758 \uc2a4\ud14c\ub85c\uc774\ub4dc \uce58\ub8cc\ub97c \uc911\ub2e8\ud558\ub294 \uacfc\uac10\ud55c \uc870\uce58\ub97c \ucde8\ud588\uc2b5\ub2c8\ub2e4. \ub2f9\uc2dc\uc5d0\ub294 \uace0\uc704\ud5d8\uc73c\ub85c \uac04\uc8fc\ub418\uc5c8\uc9c0\ub9cc, \uac70\ubd80 \ubc18\uc751\ub960\uc740 \ub0ae\uc558\uace0 \ud658\uc790\ub4e4\uc740 \uc2a4\ud14c\ub85c\uc774\ub4dc\uc758 \ubd80\uc791\uc6a9\uc744 \ud53c\ud560 \uc218 \uc788\uc5c8\uc2b5\ub2c8\ub2e4. \uc624\ub298\ub0a0, \uc2a4\ud14c\ub85c\uc774\ub4dc\ub97c \uc0ac\uc6a9\ud558\uc9c0 \uc54a\ub294 \ud504\ub85c\ud1a0\ucf5c\uc740 \uc804 \uc138\uacc4 \uc18c\uc544 \uc2e0\uc7a5 \uc774\uc2dd\uc758 \ud45c\uc900 \uce58\ub8cc\ubc95\uc73c\ub85c \uc790\ub9ac \uc7a1\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<h2>9. \uce58\uba85\uc801\uc778 \ubc14\uc774\ub7ec\uc2a4\uc640\uc758 \uc2f8\uc6c0<\/h2>\n<p>\uba74\uc5ed \uc5b5\uc81c\uc81c\ub97c \ub108\ubb34 \ub9ce\uc774 \ubcf5\uc6a9\ud558\uba74 \ubc31\ud608\uad6c\uc554\uc744 \uc720\ubc1c\ud560 \uc218 \uc788\ub294 \uc5e1\uc2a4\ud0c0\uc778-\ubc14 \ubc14\uc774\ub7ec\uc2a4\ub098 \uc774\uc2dd\ub41c \uc2e0\uc7a5\uc744 \ud30c\uad34\ud558\ub294 BK \ubc14\uc774\ub7ec\uc2a4\uc640 \uac19\uc740 \uce58\uba85\uc801\uc778 \uac10\uc5fc\uc744 \uc720\ubc1c\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ubbf8\uad6d \uad6d\ub9bd\ubcf4\uac74\uc6d0(NIH)\uacfc \ubbfc\uac04 \uae30\uc99d\uc790\ub4e4\uc758 \uc9c0\uc6d0\uc744 \ubc14\ud0d5\uc73c\ub85c \uc5f0\uad6c\uc790\ub4e4\uc740 \ubc14\uc774\ub7ec\uc2a4\ub97c \ub354 \uc798 \uc774\ud574\ud558\uace0, \uace0\uc704\ud5d8\uad70 \ud658\uc790\ub97c \ud30c\uc545\ud558\uba70, \uc774\ub7ec\ud55c \uc704\ud5d8\ud55c \uac10\uc5fc \uc704\ud5d8\uc744 \uadfc\uc808\ud558\uae30 \uc704\ud574 \ub178\ub825\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<h2>10. \uc904\uae30\uc138\ud3ec \uce58\ub8cc<\/h2>\n<p>\uc5b8\uc820\uac00 \uac04 \uc904\uae30\uc138\ud3ec\uac00 \uac04 \uc774\uc2dd\uc758 \ub300\uc548\uc73c\ub85c \uc0ac\uc6a9\ub420 \uc218 \uc788\uc744 \uac83\uc785\ub2c8\ub2e4. \uc57c\uc2ec\ucc2c \uacc4\ud68d\uc774\uc9c0\ub9cc, \ubaa9\ud45c\ub294 \uae09\uc131 \uc804\uaca9\uc131 \uac04\uc5fc \uc18c\uc544 \ud658\uc790\uc758 \uac04\uc774 \ud68c\ubcf5\ub420 \ub54c\uae4c\uc9c0 \ubcf4\uc870 \uc694\ubc95\uc73c\ub85c \uac04 \uc904\uae30\uc138\ud3ec\ub97c 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