{"id":22766,"date":"2025-12-15T07:50:18","date_gmt":"2025-12-15T15:50:18","guid":{"rendered":"https:\/\/lpfch.org\/?p=22766"},"modified":"2025-12-19T07:56:55","modified_gmt":"2025-12-19T15:56:55","slug":"isa-elaine-foundation","status":"publish","type":"post","link":"https:\/\/lpfch.org\/tl\/impact-stories\/isa-elaine-foundation\/","title":{"rendered":"Pinabilis ng Isa Elaine Foundation ang Pananaliksik sa BPAN sa Stanford School of Medicine\u00a0"},"content":{"rendered":"<p><span data-contrast=\"none\">Noon pa mang anim na buwang gulang si Isa Elaine, alam na nina Chris at Rachel Lazzara na may mali sa kanilang anak na babae. Medyo nahuhuli ang kanyang pisikal na pag-unlad sa kanyang dalawang nakatatandang kapatid na babae. Inirekomenda ng mga doktor sa kanilang bayan sa Jacksonville, Florida ang physical therapy at minomonitor ang kanyang pag-unlad. <\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">Ilang linggo lamang matapos ang kanyang unang kaarawan, ipinakita ng isang abnormal na MRI na si Isa Elaine ay may beta-propeller protein-associated neurodegeneration (BPAN), isang bihira at progresibong neurodegenerative disease.\u00a0<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">Determinadong gumawa ng pagbabago, itinatag ni Chris ang <\/span><a href=\"https:\/\/isaelaine.org\/\"><span data-contrast=\"none\">Pundasyon ni Isa Elaine<\/span><\/a><span data-contrast=\"none\"> noong 2024 upang isulong ang pananaliksik para sa BPAN at iba pang mga sakit na neurodegenerative. Kamakailan ay nagbigay ang Foundation ng isang malaking donasyon na $500,000 upang ilunsad ang Isa Elaine Foundation Research Fund sa <\/span><a href=\"https:\/\/med.stanford.edu\/profiles\/juliet-knowles\"><span data-contrast=\"none\">Stanford School of Medicine<\/span><\/a><span data-contrast=\"none\">.\u00a0<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">\u201cWalang makapaghahanda sa iyo para malaman na ang iyong anak ay may sakit na walang lunas,\u201d sabi ni Chris. \u201cMatapos masuri ang aking anak na babae, agad kaming nagsimulang maghanap ng mga kasagutan, kung paano namin nalaman ang tungkol sa magandang pananaliksik na nagaganap sa Stanford.\u201d\u00a0<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">Susuportahan ng Isa Elaine Foundation Research Fund ang<\/span><span data-contrast=\"none\"> gawaing pinangungunahan ni <\/span><a href=\"https:\/\/med.stanford.edu\/profiles\/juliet-knowles\"><span data-contrast=\"none\">Juliet Knowles, MD, PhD<\/span><\/a><span data-contrast=\"none\">, katulong na propesor ng neurolohiya at agham na neurolohikal at ng pedyatrya, <\/span><span data-contrast=\"none\">upang mapabilis ang pagbuo ng mga paggamot para sa mga batang may BPAN<\/span><span data-contrast=\"none\">Sa kasalukuyan, walang lunas o lunas para sa BPAN, na maaaring humantong sa motor dysfunction, cognitive decline, seizures, at pinaikling lifespan. Nangunguna ang Stanford sa pananaliksik sa BPAN, dahil sa malalim nitong kadalubhasaan sa mga pangunahing larangan tulad ng neurodevelopment, neurodegeneration, at epilepsy.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">Si Dr. Knowles ay isang manggagamot-siyentipiko na nagbibigay ng klinikal na pangangalaga para sa mga batang may epilepsy at bumuo ng isang pangkat na may mataas na kalidad sa buong mundo upang pag-aralan ang BPAN sa mga selulang nagmula sa tao at mga modelo ng hayop.<\/span><span data-contrast=\"auto\"> Susuportahan ng Isa Elaine Foundation Research Fund ang kanilang mga pagsisikap na isulong <\/span><span data-contrast=\"none\">isang kauna-unahang plano upang matukoy ang mga potensyal na paggamot na maaaring mabilis na maipasa sa mga klinikal na pagsubok. Kasama sa screening na ito ang mga gamot na inaprubahan ng FDA na maaaring magamit muli para sa paggamot ng BPAN.\u00a0<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">Dahil sa regalong ito, sina Chris at ang Isa Elaine Foundation ay sumasama sa iba pang mga pamilya ng mga batang may BPAN, na nagsama-sama bilang isang maliit ngunit makapangyarihang komunidad upang suportahan ang pananaliksik ni Dr. Knowles (basahin <\/span><a href=\"https:\/\/lpfch.org\/impact-stories\/two-families-with-one-goal-find-bpan-treatments\/\"><span data-contrast=\"none\">kanilang mga kwento<\/span><\/a><span data-contrast=\"none\">).\u00a0\u00a0\u00a0\u00a0<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">Bukod sa BPAN, ang kanyang pananaliksik ay may potensyal na makinabang sa iba pang mga bihirang sakit sa bata at mas karaniwang mga sakit sa neurological tulad ng Parkinson&#039;s at Alzheimer&#039;s. Ang mga pananaw mula sa pananaliksik sa BPAN ay maaaring sa huli ay magbigay ng impormasyon sa mga pamamaraan na nagpapabuti sa kalusugan ng utak sa buong buhay.\u00a0<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;201341983&quot;:0,&quot;335551550&quot;:1,&quot;335551620&quot;:1,&quot;335559685&quot;:0,&quot;335559737&quot;:0,&quot;335559738&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:278}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">Sa edad na 2, si Isa Elaine ay maaaring ang pinakabatang taong nasuring may BPAN, at siya na ang inspirasyon sa likod ng pananaliksik na maaaring magpabago ng hindi mabilang na buhay.\u00a0\u00a0<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>","protected":false},"excerpt":{"rendered":"<p>Noon pa mang anim na buwang gulang si Isa Elaine, alam na nina Chris at Rachel Lazzara na may mali sa kanilang anak. Ang kanyang pisikal na paglaki\u2026<\/p>","protected":false},"author":8,"featured_media":22767,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"categories":[21],"class_list":["post-22766","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-donor-stories"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.3 (Yoast SEO v27.3) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Isa Elaine Foundation Accelerates BPAN Research at the Stanford School of Medicine\u00a0 - Lucile Packard Foundation for Children&#039;s Health<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/lpfch.org\/tl\/impact-stories\/isa-elaine-foundation\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Isa Elaine Foundation Accelerates BPAN Research at the Stanford School of Medicine\u00a0\" \/>\n<meta property=\"og:description\" content=\"As early as when Isa Elaine was 6 months old, Chris and Rachel Lazzara knew something wasn\u2019t quite right with their daughter. 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