{"id":19368,"date":"2024-11-20T17:57:48","date_gmt":"2024-11-20T17:57:48","guid":{"rendered":"https:\/\/lpfch.org\/?p=19368"},"modified":"2025-05-22T19:40:59","modified_gmt":"2025-05-22T19:40:59","slug":"mapping-the-human-heart-cell-by-cell","status":"publish","type":"post","link":"https:\/\/lpfch.org\/vi\/impact-stories\/mapping-the-human-heart-cell-by-cell\/","title":{"rendered":"L\u1eadp b\u1ea3n \u0111\u1ed3 tim ng\u01b0\u1eddi, t\u1eebng t\u1ebf b\u00e0o m\u1ed9t"},"content":{"rendered":"

Ti\u1ebfn s\u0129 Xiaojie Qiu tham gia s\u00e1ng ki\u1ebfn t\u00e1o b\u1ea1o c\u1ee7a Stanford nh\u1eb1m ch\u1eefa b\u1ec7nh tim b\u1ea9m sinh<\/h4>\n

L\u1edbn l\u00ean t\u1ea1i m\u1ed9t th\u1ecb tr\u1ea5n h\u1ebbo l\u00e1nh \u1edf v\u00f9ng n\u00f4ng th\u00f4n Trung Qu\u1ed1c, cu\u1ed9c s\u1ed1ng thu\u1edf nh\u1ecf c\u1ee7a Xiaojie Qiu g\u1eafn li\u1ec1n v\u1edbi nh\u1eefng kh\u00f3 kh\u0103n. N\u0103m 10 tu\u1ed5i, cha anh qua \u0111\u1eddi trong m\u1ed9t tai n\u1ea1n lao \u0111\u1ed9ng. Anh \u0111\u01b0\u1ee3c g\u1eedi v\u1ec1 s\u1ed1ng v\u1edbi \u00f4ng b\u00e0 ngo\u1ea1i, nh\u1eefng ng\u01b0\u1eddi tuy ngh\u00e8o kh\u00f3 nh\u01b0ng lu\u00f4n \u01b0u ti\u00ean vi\u1ec7c h\u1ecdc cho anh.<\/p>\n

\u201cH\u1ecd l\u00e0 nh\u1eefng \u00f4ng b\u00e0 tuy\u1ec7t v\u1eddi nh\u1ea5t tr\u00ean \u0111\u1eddi,\u201d Qiu nh\u1edb l\u1ea1i. \u201cH\u1ecd kh\u00f4ng \u0111\u01b0\u1ee3c h\u1ecdc h\u00e0nh t\u1eed t\u1ebf, nh\u01b0ng h\u1ecd tr\u00e2n tr\u1ecdng t\u1ea7m quan tr\u1ecdng c\u1ee7a gi\u00e1o d\u1ee5c v\u00e0 \u1ee7ng h\u1ed9 t\u00f4i theo \u0111u\u1ed5i \u01b0\u1edbc m\u01a1.\u201d<\/p>\n

Qiu h\u1ecdc r\u1ea5t gi\u1ecfi, d\u00e0nh t\u1edbi 16 ti\u1ebfng m\u1ed7i ng\u00e0y \u0111\u1ec3 h\u1ecdc v\u00e0 gi\u00e0nh \u0111\u01b0\u1ee3c su\u1ea5t v\u00e0o m\u1ed9t tr\u01b0\u1eddng h\u00e0ng \u0111\u1ea7u trong khu v\u1ef1c. Ni\u1ec1m \u0111am m\u00ea khoa h\u1ecdc c\u1ee7a anh d\u1ea7n n\u1ea3y n\u1edf, v\u00e0 h\u00e0nh tr\u00ecnh h\u1ecdc t\u1eadp \u0111\u00e3 \u0111\u01b0a anh \u0111\u1ebfn Hoa K\u1ef3, n\u01a1i nghi\u00ean c\u1ee9u c\u1ee7a anh thu h\u00fat s\u1ef1 ch\u00fa \u00fd c\u1ee7a c\u1ea3 n\u01b0\u1edbc, \u0111\u01b0\u1ee3c l\u00ean trang b\u00eca c\u1ee7a t\u1ea1p ch\u00ed uy t\u00edn Cell.<\/p>\n

V\u00e0o th\u00e1ng 12 n\u0103m 2023, Qiu \u0111\u1ebfn Stanford, tr\u1edf th\u00e0nh th\u00e0nh vi\u00ean th\u1ee9 t\u01b0 c\u1ee7a S\u00e1ng ki\u1ebfn Khoa h\u1ecdc v\u00e0 K\u1ef9 thu\u1eadt C\u01a1 b\u1ea3n (BASE) thu\u1ed9c Trung t\u00e2m Tim m\u1ea1ch Tr\u1ebb em Betty Irene Moore, m\u1ed9t ch\u01b0\u01a1ng tr\u00ecnh nghi\u00ean c\u1ee9u \u0111\u1ed9c \u0111\u00e1o nh\u1eb1m m\u1ee5c \u0111\u00edch t\u00ecm hi\u1ec3u v\u00e0 cu\u1ed1i c\u00f9ng l\u00e0 ch\u1eefa kh\u1ecfi b\u1ec7nh tim b\u1ea9m sinh (CHD). BASE t\u1eadp h\u1ee3p c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u t\u1eeb nhi\u1ec1u l\u0129nh v\u1ef1c khoa h\u1ecdc kh\u00e1c nhau, c\u00f9ng nhau h\u1ee3p t\u00e1c t\u00ecm ra nh\u1eefng ph\u01b0\u01a1ng ph\u00e1p m\u1edbi \u0111\u1ec3 gi\u1ea3i quy\u1ebft CHD, c\u0103n b\u1ec7nh \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn 1\/100 tr\u1ebb s\u01a1 sinh t\u1ea1i Hoa K\u1ef3.<\/p>\n

L\u00e0 tr\u1ee3 l\u00fd gi\u00e1o s\u01b0 v\u1ec1 di truy\u1ec1n h\u1ecdc v\u00e0 khoa h\u1ecdc m\u00e1y t\u00ednh, Qiu \u0111ang s\u1eed d\u1ee5ng h\u1ec7 gen t\u1ebf b\u00e0o \u0111\u01a1n v\u00e0 h\u1ecdc m\u00e1y \u0111\u1ec3 gi\u1ea3i quy\u1ebft nh\u1eefng th\u00e1ch th\u1ee9c then ch\u1ed1t trong nghi\u00ean c\u1ee9u tim m\u1ea1ch. Nh\u1eefng ti\u1ebfn b\u1ed9 g\u1ea7n \u0111\u00e2y cho ph\u00e9p nghi\u00ean c\u1ee9u h\u00e0ng tri\u1ec7u t\u1ebf b\u00e0o c\u00f9ng l\u00fac \u0111\u1ec3 hi\u1ec3u c\u00e1ch th\u1ee9c h\u00ecnh th\u00e0nh c\u00e1c c\u01a1 quan. Tuy nhi\u00ean, v\u1eabn ch\u01b0a th\u1ec3 bi\u1ebft ch\u00ednh x\u00e1c v\u1ecb tr\u00ed c\u1ee7a t\u1eebng t\u1ebf b\u00e0o trong c\u01a1 quan v\u00e0 theo d\u00f5i c\u00e1c t\u1ebf b\u00e0o theo th\u1eddi gian. Qiu \u0111ang ti\u00ean phong trong c\u00e1c ph\u01b0\u01a1ng ph\u00e1p ti\u1ebfp c\u1eadn \u0111\u1ec3 v\u01b0\u1ee3t qua nh\u1eefng tr\u1edf ng\u1ea1i n\u00e0y v\u00e0 gi\u00fap c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u t\u1ea1o ra m\u1ed9t b\u1ea3n \u0111\u1ed3 - t\u01b0\u01a1ng t\u1ef1 nh\u01b0 Google Earth - m\u00f4 t\u1ea3 v\u1ecb tr\u00ed v\u00e0 th\u1eddi \u0111i\u1ec3m ph\u00e1t tri\u1ec3n b\u1ec7nh tim \u1edf c\u1ea5p \u0111\u1ed9 t\u1ebf b\u00e0o.<\/p>\n

\u201cKhi m\u1edbi b\u1eaft \u0111\u1ea7u, t\u00f4i bi\u1ebft r\u1eb1ng \u0111\u1ec3 hi\u1ec3u v\u1ec1 b\u1ec7nh tim, ch\u00fang ta c\u1ea7n bi\u1ebft khi n\u00e0o v\u00e0 \u1edf \u0111\u00e2u c\u00e1c gen b\u1eaft \u0111\u1ea7u ho\u1ea1t \u0111\u1ed9ng kh\u00e1c so v\u1edbi \u1edf m\u1ed9t tr\u00e1i tim kh\u1ecfe m\u1ea1nh,\u201d Qiu n\u00f3i. \u201c\u0110\u1ec3 c\u00f3 \u0111\u01b0\u1ee3c c\u00e2u tr\u1ea3 l\u1eddi \u0111\u00f3, c\u1ea7n ph\u1ea3i nghi\u00ean c\u1ee9u h\u00e0ng tri\u1ec7u t\u1ebf b\u00e0o v\u00e0 h\u00e0ng ngh\u00ecn gen tr\u00ean m\u1ed7i t\u1ebf b\u00e0o theo th\u1eddi gian v\u00e0 kh\u00f4ng gian. Ph\u01b0\u01a1ng ph\u00e1p c\u1ee7a t\u00f4i cho ph\u00e9p ch\u00fang t\u00f4i l\u1ea7n \u0111\u1ea7u ti\u00ean theo d\u00f5i c\u00e1c gen \u0111\u01b0\u1ee3c bi\u1ec3u hi\u1ec7n b\u1edfi t\u1eebng t\u1ebf b\u00e0o ri\u00eang l\u1ebb, \u0111i\u1ec1u n\u00e0y s\u1ebd gi\u00fap ch\u00fang t\u00f4i bi\u1ebft t\u1ebf b\u00e0o n\u00e0o li\u00ean quan \u0111\u1ebfn b\u1ec7nh tim v\u00e0 ch\u00ednh x\u00e1c l\u00e0 \u1edf giai \u0111o\u1ea1n n\u00e0o trong qu\u00e1 tr\u00ecnh ph\u00e1t tri\u1ec3n c\u1ee7a tim.\u201d<\/p>\n

Nghi\u00ean c\u1ee9u c\u1ee7a Qiu s\u1ebd cung c\u1ea5p cho c\u00e1c th\u00e0nh vi\u00ean c\u00f2n l\u1ea1i c\u1ee7a nh\u00f3m BASE nh\u1eefng hi\u1ec3u bi\u1ebft m\u1edbi m\u1ebb v\u00e0 s\u00e2u s\u1eafc \u0111\u1ec3 \u00e1p d\u1ee5ng v\u00e0o c\u00f4ng vi\u1ec7c c\u1ee7a h\u1ecd.<\/p>\n

Ti\u1ebfn s\u0129 Marlene Rabinovitch, gi\u00e1m \u0111\u1ed1c BASE v\u00e0 Gi\u00e1o s\u01b0 Tim m\u1ea1ch Nhi khoa Dwight v\u00e0 Vera Dunlevie, r\u1ea5t h\u00e0o h\u1ee9ng v\u1edbi ki\u1ebfn th\u1ee9c m\u00e0 Qiu mang l\u1ea1i. "Xiaojie \u0111ang l\u00e0m m\u1ed9t \u0111i\u1ec1u ch\u01b0a t\u1eebng c\u00f3 tr\u01b0\u1edbc \u0111\u00e2y", Rabinovitch n\u00f3i. "Chuy\u00ean m\u00f4n \u0111\u1ed9c \u0111\u00e1o c\u1ee7a anh \u1ea5y, c\u00f9ng v\u1edbi c\u00e1ch n\u00f3 b\u1ed5 sung cho c\u00f4ng vi\u1ec7c c\u1ee7a to\u00e0n b\u1ed9 \u0111\u1ed9i ng\u0169 BASE, t\u1ea1o ra ti\u1ec1m n\u0103ng bi\u1ebfn \u0111\u1ed5i l\u0129nh v\u1ef1c n\u00e0y v\u00e0 thay \u0111\u1ed5i cu\u1ed9c s\u1ed1ng c\u1ee7a r\u1ea5t nhi\u1ec1u tr\u1ebb em."<\/p>\n

Ti\u1ebfn s\u0129 Mark Skylar-Scott, nh\u00e0 khoa h\u1ecdc \u0111\u1ed3ng nghi\u1ec7p c\u1ee7a BASE, r\u1ea5t h\u00e0o h\u1ee9ng tr\u01b0\u1edbc ti\u1ec1m n\u0103ng nghi\u00ean c\u1ee9u c\u1ee7a Qiu. "L\u00e0 m\u1ed9t k\u1ef9 s\u01b0 in sinh h\u1ecdc 3D, t\u00f4i coi b\u1ea3n \u0111\u1ed3 c\u1ee7a Xiaojie nh\u01b0 c\u1ea9m nang h\u01b0\u1edbng d\u1eabn c\u00e1ch t\u1ea1o ra m\u1ed9t tr\u00e1i tim", Skylar-Scott n\u00f3i. "Kh\u1ea3 n\u0103ng t\u00ednh to\u00e1n tuy\u1ec7t v\u1eddi c\u1ee7a anh \u1ea5y l\u00e0 n\u1ec1n t\u1ea3ng cho th\u00e0nh c\u00f4ng c\u1ee7a BASE."<\/p>\n

Hi\u1ec7n t\u1ea1i, Qiu \u0111ang t\u1eadp trung v\u00e0o vi\u1ec7c \u1ee9ng d\u1ee5ng c\u00f4ng ngh\u1ec7 m\u1edbi c\u1ee7a m\u00ecnh \u0111\u1ec3 t\u1ea1o ra b\u1ea3n \u0111\u1ed3 3D v\u1ec1 tim chu\u1ed9t, t\u1eeb giai \u0111o\u1ea1n \u0111\u1ea7u \u0111\u1ebfn khi ho\u00e0n thi\u1ec7n. Anh \u0111\u1eb7t m\u1ee5c ti\u00eau t\u01b0\u01a1ng t\u1ef1 v\u1edbi ph\u00f4i thai ng\u01b0\u1eddi.<\/p>\n

G\u1ea7n \u0111\u00e2y, Qiu \u0111\u00e3 nh\u1eadn \u0111\u01b0\u1ee3c m\u1ed9t m\u00f3n qu\u00e0 h\u00e0o ph\u00f3ng t\u1eeb c\u00e1c nh\u00e0 h\u1ea3o t\u00e2m Pantas Sutardja v\u00e0 Ting Chuk \u0111\u1ec3 h\u1ed7 tr\u1ee3 d\u1ef1 \u00e1n n\u00e0y. "Ch\u00fang t\u00f4i r\u1ea5t vui m\u1eebng \u0111\u01b0\u1ee3c h\u1ee3p t\u00e1c v\u1edbi Xiaojie trong c\u00f4ng tr\u00ecnh ti\u00ean phong c\u1ee7a anh \u1ea5y nh\u1eb1m m\u1edf ra nh\u1eefng hi\u1ec3u bi\u1ebft m\u1edbi v\u1ec1 b\u1ec7nh tim b\u1ea9m sinh", Sutardja v\u00e0 Chuk chia s\u1ebb. "Ch\u00fang t\u00f4i r\u1ea5t mong ch\u1edd \u0111\u01b0\u1ee3c ch\u1ee9ng ki\u1ebfn nh\u1eefng th\u00e0nh t\u1ef1u m\u00e0 Xiaojie v\u00e0 to\u00e0n b\u1ed9 \u0111\u1ed9i ng\u0169 BASE s\u1ebd \u0111\u1ea1t \u0111\u01b0\u1ee3c trong nh\u1eefng n\u0103m t\u1edbi."<\/p>\n

\u201cT\u00f4i v\u00f4 c\u00f9ng bi\u1ebft \u01a1n khi \u0111\u01b0\u1ee3c \u1edf \u0111\u00e2y, \u0111\u01b0\u1ee3c l\u00e0m vi\u1ec7c v\u1edbi c\u00e1c nh\u00e0 khoa h\u1ecdc l\u1ed7i l\u1ea1c \u0111\u1ec3 gi\u1ea3i quy\u1ebft nh\u1eefng v\u1ea5n \u0111\u1ec1 l\u1edbn,\u201d Qiu n\u00f3i. \u201cT\u00f4i bi\u1ebft \u01a1n gia \u0111\u00ecnh \u0111\u00e3 \u1ee7ng h\u1ed9 t\u00f4i \u0111\u1ebfn \u0111\u01b0\u1ee3c \u0111\u00e2y, v\u00e0 t\u1ef1 h\u00e0o v\u00ec \u0111\u00e3 v\u01b0\u1ee3t qua nh\u1eefng tr\u1edf ng\u1ea1i v\u00e0 \u0111\u1ea1t \u0111\u01b0\u1ee3c \u01b0\u1edbc m\u01a1 c\u1ee7a m\u00ecnh.\u201d<\/p>\n

B\u00e0i vi\u1ebft n\u00e0y ban \u0111\u1ea7u xu\u1ea5t hi\u1ec7n trong \u1ea5n b\u1ea3n M\u00f9a thu n\u0103m 2024 c\u1ee7a Tin t\u1ee9c Tr\u1ebb em Packard<\/a>.<\/p>","protected":false},"excerpt":{"rendered":"

Ti\u1ebfn s\u0129 Xiaojie Qiu tham gia s\u00e1ng ki\u1ebfn t\u00e1o b\u1ea1o c\u1ee7a Stanford nh\u1eb1m ch\u1eefa b\u1ec7nh tim b\u1ea9m sinh L\u1edbn l\u00ean \u1edf m\u1ed9t th\u1ecb tr\u1ea5n xa x\u00f4i \u1edf v\u00f9ng n\u00f4ng th\u00f4n Trung Qu\u1ed1c, cu\u1ed9c s\u1ed1ng th\u1eddi th\u01a1 \u1ea5u c\u1ee7a Xiaojie Qiu\u2026<\/p>","protected":false},"author":7,"featured_media":19370,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"categories":[148,164],"class_list":["post-19368","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-in-the-news","category-research","health_topic-heart"],"acf":[],"yoast_head":"\nMapping the Human Heart, Cell by Cell - Lucile Packard Foundation for Children's Health<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"http:\/\/lpfch.org\/vi\/impact-stories\/mapping-the-human-heart-cell-by-cell\/\" \/>\n<meta property=\"og:locale\" content=\"vi_VN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Mapping the Human Heart, Cell by Cell\" \/>\n<meta property=\"og:description\" content=\"Xiaojie Qiu, PhD, joins Stanford\u2019s bold initiative to cure congenital heart disease Growing up in a remote town in rural China, Xiaojie Qiu\u2019s early life...\" \/>\n<meta property=\"og:url\" content=\"http:\/\/lpfch.org\/vi\/impact-stories\/mapping-the-human-heart-cell-by-cell\/\" \/>\n<meta property=\"og:site_name\" content=\"Lucile Packard Foundation for Children's Health\" \/>\n<meta property=\"article:published_time\" content=\"2024-11-20T17:57:48+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2025-05-22T19:40:59+00:00\" \/>\n<meta property=\"og:image\" content=\"http:\/\/lpfch.org\/wp-content\/uploads\/2024\/11\/570A9641-e1732125253485-809x1024.png\" \/>\n\t<meta property=\"og:image:width\" content=\"809\" \/>\n\t<meta property=\"og:image:height\" content=\"1024\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"brian.pendergast\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"brian.pendergast\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"http:\/\/lpfch.org\/zh\/impact-stories\/mapping-the-human-heart-cell-by-cell\/#article\",\"isPartOf\":{\"@id\":\"http:\/\/lpfch.org\/zh\/impact-stories\/mapping-the-human-heart-cell-by-cell\/\"},\"author\":{\"name\":\"brian.pendergast\",\"@id\":\"https:\/\/lpfch.org\/km\/#\/schema\/person\/9895de43ccd8af24fe591c84bb4d5d07\"},\"headline\":\"Mapping the Human Heart, Cell by Cell\",\"datePublished\":\"2024-11-20T17:57:48+00:00\",\"dateModified\":\"2025-05-22T19:40:59+00:00\",\"mainEntityOfPage\":{\"@id\":\"http:\/\/lpfch.org\/zh\/impact-stories\/mapping-the-human-heart-cell-by-cell\/\"},\"wordCount\":678,\"image\":{\"@id\":\"http:\/\/lpfch.org\/zh\/impact-stories\/mapping-the-human-heart-cell-by-cell\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/lpfch.org\/wp-content\/uploads\/2024\/11\/570A9641-e1732125253485.png\",\"articleSection\":[\"In the News\",\"Research\"],\"inLanguage\":\"vi\"},{\"@type\":\"WebPage\",\"@id\":\"http:\/\/lpfch.org\/zh\/impact-stories\/mapping-the-human-heart-cell-by-cell\/\",\"url\":\"http:\/\/lpfch.org\/zh\/impact-stories\/mapping-the-human-heart-cell-by-cell\/\",\"name\":\"Mapping the Human Heart, Cell by Cell - 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