{"id":22766,"date":"2025-12-15T07:50:18","date_gmt":"2025-12-15T15:50:18","guid":{"rendered":"https:\/\/lpfch.org\/?p=22766"},"modified":"2025-12-19T07:56:55","modified_gmt":"2025-12-19T15:56:55","slug":"isa-elaine-foundation","status":"publish","type":"post","link":"https:\/\/lpfch.org\/vi\/impact-stories\/isa-elaine-foundation\/","title":{"rendered":"Qu\u1ef9 Isa Elaine th\u00fac \u0111\u1ea9y nghi\u00ean c\u1ee9u BPAN t\u1ea1i Tr\u01b0\u1eddng Y khoa Stanford.\u00a0"},"content":{"rendered":"<p><span data-contrast=\"none\">Ngay t\u1eeb khi Isa Elaine m\u1edbi 6 th\u00e1ng tu\u1ed5i, Chris v\u00e0 Rachel Lazzara \u0111\u00e3 bi\u1ebft c\u00f3 \u0111i\u1ec1u g\u00ec \u0111\u00f3 kh\u00f4ng \u1ed5n v\u1edbi con g\u00e1i h\u1ecd. S\u1ef1 ph\u00e1t tri\u1ec3n th\u1ec3 ch\u1ea5t c\u1ee7a b\u00e9 ch\u1eadm h\u01a1n m\u1ed9t ch\u00fat so v\u1edbi hai ch\u1ecb g\u00e1i l\u1edbn h\u01a1n. C\u00e1c b\u00e1c s\u0129 \u1edf qu\u00ea nh\u00e0 Jacksonville, Florida, \u0111\u00e3 khuy\u00ean n\u00ean cho b\u00e9 t\u1eadp v\u1eadt l\u00fd tr\u1ecb li\u1ec7u v\u00e0 theo d\u00f5i ti\u1ebfn tr\u00ecnh h\u1ed3i ph\u1ee5c c\u1ee7a b\u00e9. <\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">Ch\u1ec9 v\u00e0i tu\u1ea7n sau sinh nh\u1eadt \u0111\u1ea7u ti\u00ean, k\u1ebft qu\u1ea3 ch\u1ee5p c\u1ed9ng h\u01b0\u1edfng t\u1eeb (MRI) b\u1ea5t th\u01b0\u1eddng cho th\u1ea5y Isa Elaine m\u1eafc ch\u1ee9ng tho\u00e1i h\u00f3a th\u1ea7n kinh li\u00ean quan \u0111\u1ebfn protein beta-propeller (BPAN), m\u1ed9t c\u0103n b\u1ec7nh tho\u00e1i h\u00f3a th\u1ea7n kinh hi\u1ebfm g\u1eb7p v\u00e0 ti\u1ebfn tri\u1ec3n.\u00a0<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">V\u1edbi quy\u1ebft t\u00e2m t\u1ea1o ra s\u1ef1 kh\u00e1c bi\u1ec7t, Chris \u0111\u00e3 th\u00e0nh l\u1eadp t\u1ed5 ch\u1ee9c n\u00e0y. <\/span><a href=\"https:\/\/isaelaine.org\/\"><span data-contrast=\"none\">Qu\u1ef9 Isa Elaine<\/span><\/a><span data-contrast=\"none\"> N\u0103m 2024, Qu\u1ef9 Isa Elaine s\u1ebd th\u00fac \u0111\u1ea9y nghi\u00ean c\u1ee9u v\u1ec1 BPAN v\u00e0 c\u00e1c b\u1ec7nh tho\u00e1i h\u00f3a th\u1ea7n kinh kh\u00e1c. G\u1ea7n \u0111\u00e2y, Qu\u1ef9 \u0111\u00e3 h\u00e0o ph\u00f3ng t\u1eb7ng 1.450.000 b\u1ea3ng Anh \u0111\u1ec3 th\u00e0nh l\u1eadp Qu\u1ef9 Nghi\u00ean c\u1ee9u Isa Elaine. <\/span><a href=\"https:\/\/med.stanford.edu\/profiles\/juliet-knowles\"><span data-contrast=\"none\">Tr\u01b0\u1eddng Y khoa Stanford<\/span><\/a><span data-contrast=\"none\">.\u00a0<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">\u201cKh\u00f4ng g\u00ec c\u00f3 th\u1ec3 chu\u1ea9n b\u1ecb cho b\u1ea1n tr\u01b0\u1edbc vi\u1ec7c bi\u1ebft con m\u00ecnh m\u1eafc m\u1ed9t c\u0103n b\u1ec7nh nan y,\u201d Chris n\u00f3i. \u201cSau khi con g\u00e1i t\u00f4i \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n, ch\u00fang t\u00f4i ngay l\u1eadp t\u1ee9c b\u1eaft \u0111\u1ea7u t\u00ecm ki\u1ebfm c\u00e2u tr\u1ea3 l\u1eddi, v\u00e0 \u0111\u00f3 l\u00e0 c\u00e1ch ch\u00fang t\u00f4i bi\u1ebft \u0111\u1ebfn nh\u1eefng nghi\u00ean c\u1ee9u \u0111\u1ea7y h\u1ee9a h\u1eb9n \u0111ang di\u1ec5n ra t\u1ea1i Stanford.\u201d\u00a0<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">Qu\u1ef9 nghi\u00ean c\u1ee9u c\u1ee7a T\u1ed5 ch\u1ee9c Isa Elaine s\u1ebd h\u1ed7 tr\u1ee3<\/span><span data-contrast=\"none\"> c\u00f4ng vi\u1ec7c do <\/span><a href=\"https:\/\/med.stanford.edu\/profiles\/juliet-knowles\"><span data-contrast=\"none\">Juliet Knowles, MD, PhD<\/span><\/a><span data-contrast=\"none\">, tr\u1ee3 l\u00fd gi\u00e1o s\u01b0 v\u1ec1 th\u1ea7n kinh h\u1ecdc v\u00e0 khoa h\u1ecdc th\u1ea7n kinh, \u0111\u1ed3ng th\u1eddi l\u00e0 tr\u1ee3 l\u00fd gi\u00e1o s\u01b0 v\u1ec1 nhi khoa. <\/span><span data-contrast=\"none\">nh\u1eb1m \u0111\u1ea9y nhanh qu\u00e1 tr\u00ecnh ph\u00e1t tri\u1ec3n c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb cho tr\u1ebb em m\u1eafc BPAN.<\/span><span data-contrast=\"none\">Hi\u1ec7n t\u1ea1i, ch\u01b0a c\u00f3 ph\u01b0\u01a1ng ph\u00e1p ch\u1eefa tr\u1ecb hay \u0111i\u1ec1u tr\u1ecb n\u00e0o cho BPAN, c\u0103n b\u1ec7nh c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn r\u1ed1i lo\u1ea1n v\u1eadn \u0111\u1ed9ng, suy gi\u1ea3m nh\u1eadn th\u1ee9c, co gi\u1eadt v\u00e0 gi\u1ea3m tu\u1ed5i th\u1ecd. \u0110\u1ea1i h\u1ecdc Stanford l\u00e0 \u0111\u01a1n v\u1ecb d\u1eabn \u0111\u1ea7u trong nghi\u00ean c\u1ee9u v\u1ec1 BPAN, nh\u1edd v\u00e0o chuy\u00ean m\u00f4n s\u00e2u r\u1ed9ng trong c\u00e1c l\u0129nh v\u1ef1c quan tr\u1ecdng nh\u01b0 ph\u00e1t tri\u1ec3n th\u1ea7n kinh, tho\u00e1i h\u00f3a th\u1ea7n kinh v\u00e0 \u0111\u1ed9ng kinh.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">Ti\u1ebfn s\u0129 Knowles l\u00e0 m\u1ed9t b\u00e1c s\u0129 ki\u00eam nh\u00e0 khoa h\u1ecdc, chuy\u00ean cung c\u1ea5p d\u1ecbch v\u1ee5 ch\u0103m s\u00f3c l\u00e2m s\u00e0ng cho tr\u1ebb em m\u1eafc b\u1ec7nh \u0111\u1ed9ng kinh v\u00e0 \u0111\u00e3 t\u1eadp h\u1ee3p m\u1ed9t nh\u00f3m nghi\u00ean c\u1ee9u h\u00e0ng \u0111\u1ea7u th\u1ebf gi\u1edbi \u0111\u1ec3 nghi\u00ean c\u1ee9u BPAN tr\u00ean t\u1ebf b\u00e0o c\u00f3 ngu\u1ed3n g\u1ed1c t\u1eeb ng\u01b0\u1eddi v\u00e0 m\u00f4 h\u00ecnh \u0111\u1ed9ng v\u1eadt.<\/span><span data-contrast=\"auto\"> Qu\u1ef9 nghi\u00ean c\u1ee9u c\u1ee7a T\u1ed5 ch\u1ee9c Isa Elaine s\u1ebd h\u1ed7 tr\u1ee3 nh\u1eefng n\u1ed7 l\u1ef1c c\u1ee7a h\u1ecd trong vi\u1ec7c th\u00fac \u0111\u1ea9y s\u1ef1 ph\u00e1t tri\u1ec3n n\u00e0y. <\/span><span data-contrast=\"none\">M\u1ed9t k\u1ebf ho\u1ea1ch ch\u01b0a t\u1eebng c\u00f3 ti\u1ec1n l\u1ec7 nh\u1eb1m x\u00e1c \u0111\u1ecbnh c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb ti\u1ec1m n\u0103ng c\u00f3 th\u1ec3 nhanh ch\u00f3ng ti\u1ebfn \u0111\u1ebfn th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng. Qu\u00e1 tr\u00ecnh s\u00e0ng l\u1ecdc n\u00e0y bao g\u1ed3m c\u00e1c lo\u1ea1i thu\u1ed1c \u0111\u00e3 \u0111\u01b0\u1ee3c FDA ph\u00ea duy\u1ec7t c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng l\u1ea1i \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb BPAN.\u00a0<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">V\u1edbi m\u00f3n qu\u00e0 n\u00e0y, Chris v\u00e0 Qu\u1ef9 Isa Elaine c\u00f9ng v\u1edbi c\u00e1c gia \u0111\u00ecnh kh\u00e1c c\u00f3 con m\u1eafc BPAN \u0111\u00e3 c\u00f9ng nhau t\u1ea1o n\u00ean m\u1ed9t c\u1ed9ng \u0111\u1ed3ng nh\u1ecf nh\u01b0ng m\u1ea1nh m\u1ebd \u0111\u1ec3 h\u1ed7 tr\u1ee3 nghi\u00ean c\u1ee9u c\u1ee7a Ti\u1ebfn s\u0129 Knowles (xem th\u00eam) <\/span><a href=\"https:\/\/lpfch.org\/impact-stories\/two-families-with-one-goal-find-bpan-treatments\/\"><span data-contrast=\"none\">nh\u1eefng c\u00e2u chuy\u1ec7n c\u1ee7a h\u1ecd<\/span><\/a><span data-contrast=\"none\">).\u00a0\u00a0\u00a0\u00a0<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">Ngo\u00e0i BPAN, nghi\u00ean c\u1ee9u c\u1ee7a b\u00e0 c\u00f2n c\u00f3 ti\u1ec1m n\u0103ng mang l\u1ea1i l\u1ee3i \u00edch cho c\u00e1c b\u1ec7nh nhi hi\u1ebfm g\u1eb7p kh\u00e1c v\u00e0 c\u00e1c b\u1ec7nh th\u1ea7n kinh ph\u1ed5 bi\u1ebfn h\u01a1n nh\u01b0 Parkinson v\u00e0 Alzheimer. Nh\u1eefng hi\u1ec3u bi\u1ebft t\u1eeb nghi\u00ean c\u1ee9u v\u1ec1 BPAN cu\u1ed1i c\u00f9ng c\u00f3 th\u1ec3 cung c\u1ea5p th\u00f4ng tin h\u1eefu \u00edch cho c\u00e1c ph\u01b0\u01a1ng ph\u00e1p c\u1ea3i thi\u1ec7n s\u1ee9c kh\u1ecfe n\u00e3o b\u1ed9 trong su\u1ed1t cu\u1ed9c \u0111\u1eddi.\u00a0<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;201341983&quot;:0,&quot;335551550&quot;:1,&quot;335551620&quot;:1,&quot;335559685&quot;:0,&quot;335559737&quot;:0,&quot;335559738&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:278}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">M\u1edbi 2 tu\u1ed5i, Isa Elaine c\u00f3 th\u1ec3 l\u00e0 ng\u01b0\u1eddi nh\u1ecf tu\u1ed5i nh\u1ea5t t\u1eebng \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n m\u1eafc BPAN, v\u00e0 em \u0111\u00e3 l\u00e0 ngu\u1ed3n c\u1ea3m h\u1ee9ng cho c\u00e1c nghi\u00ean c\u1ee9u c\u00f3 th\u1ec3 thay \u0111\u1ed5i cu\u1ed9c s\u1ed1ng c\u1ee7a v\u00f4 s\u1ed1 ng\u01b0\u1eddi.\u00a0\u00a0<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>","protected":false},"excerpt":{"rendered":"<p>Ngay t\u1eeb khi Isa Elaine m\u1edbi 6 th\u00e1ng tu\u1ed5i, Chris v\u00e0 Rachel Lazzara \u0111\u00e3 bi\u1ebft c\u00f3 \u0111i\u1ec1u g\u00ec \u0111\u00f3 kh\u00f4ng \u1ed5n v\u1edbi con g\u00e1i h\u1ecd. S\u1ef1 ph\u00e1t tri\u1ec3n th\u1ec3 ch\u1ea5t c\u1ee7a b\u00e9\u2026<\/p>","protected":false},"author":8,"featured_media":22767,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"categories":[21],"class_list":["post-22766","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-donor-stories"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.3 (Yoast SEO v27.3) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Isa Elaine Foundation Accelerates BPAN Research at the Stanford School of Medicine\u00a0 - Lucile Packard Foundation for Children&#039;s Health<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/lpfch.org\/vi\/impact-stories\/isa-elaine-foundation\/\" \/>\n<meta property=\"og:locale\" content=\"vi_VN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Isa Elaine Foundation Accelerates BPAN Research at the Stanford School of Medicine\u00a0\" \/>\n<meta property=\"og:description\" content=\"As early as when Isa Elaine was 6 months old, Chris and Rachel Lazzara knew something wasn\u2019t quite right with their daughter. 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