{"id":3526,"date":"2014-08-20T23:27:52","date_gmt":"2014-08-20T23:27:52","guid":{"rendered":"https:\/\/lpfch.org\/expanding-the-realm-of-possibility-10-breakthroughs-in-pediatric-organ-transplantation-pioneered-at-lucile-packard-childrens-hospital\/"},"modified":"2024-09-13T18:27:35","modified_gmt":"2024-09-13T18:27:35","slug":"expanding-the-realm-of-possibility-10-breakthroughs-in-pediatric-organ-transplantation-pioneered-at-lucile-packard-childrens-hospital","status":"publish","type":"post","link":"https:\/\/lpfch.org\/vi\/impact-stories\/expanding-the-realm-of-possibility-10-breakthroughs-in-pediatric-organ-transplantation-pioneered-at-lucile-packard-childrens-hospital\/","title":{"rendered":"M\u1edf r\u1ed9ng ph\u1ea1m vi kh\u1ea3 n\u0103ng: 10 \u0111\u1ed9t ph\u00e1 trong gh\u00e9p t\u1ea1ng nhi khoa \u0111\u01b0\u1ee3c ti\u00ean phong t\u1ea1i B\u1ec7nh vi\u1ec7n nhi Lucile Packard"},"content":{"rendered":"<p><span style=\"font-weight: bold; font-size: 1.231em; line-height: 1.538em;\">1. T\u1ed5 ch\u1ee9c l\u1edbn<\/span><span style=\"font-weight: bold; font-size: 1.231em; line-height: 1.538em;\">tr\u1ea3 l\u1eddi cho tr\u1ebb nh\u1ecf<\/span><\/p>\n<p>Ti\u1ebfn s\u0129, B\u00e1c s\u0129 Carlos Esquivel cho bi\u1ebft: &quot;Do t\u00ecnh tr\u1ea1ng thi\u1ebfu h\u1ee5t n\u1ed9i t\u1ea1ng tr\u1ea7m tr\u1ecdng \u1edf tr\u1ebb em, ch\u00fang t\u00f4i ph\u1ea3i s\u00e1ng t\u1ea1o&quot;. \u00d4ng l\u00e0 m\u1ed9t trong nh\u1eefng b\u00e1c s\u0129 ph\u1eabu thu\u1eadt \u0111\u1ea7u ti\u00ean gh\u00e9p gan t\u1eeb ng\u01b0\u1eddi hi\u1ebfn t\u1eb7ng \u0111\u00e3 qua \u0111\u1eddi b\u1eb1ng c\u00e1ch chia gan th\u00e0nh hai ph\u1ea7n c\u00f3 th\u1ec3 gh\u00e9p \u0111\u01b0\u1ee3c cho hai b\u1ec7nh nh\u00e2n \u2014 m\u1ed9t tr\u1ebb em v\u00e0 m\u1ed9t ng\u01b0\u1eddi l\u1edbn.<\/p>\n<p>Esquivel v\u00e0 c\u00e1c c\u1ed9ng s\u1ef1 c\u0169ng n\u1eb1m trong s\u1ed1 nh\u1eefng ng\u01b0\u1eddi \u0111\u1ea7u ti\u00ean gh\u00e9p th\u00e0nh c\u00f4ng m\u1ed9t ph\u1ea7n gan t\u1eeb ng\u01b0\u1eddi hi\u1ebfn t\u1eb7ng tr\u01b0\u1edfng th\u00e0nh c\u00f2n s\u1ed1ng cho m\u1ed9t \u0111\u1ee9a tr\u1ebb. \u0110i\u1ec1u \u0111\u00e1ng kinh ng\u1ea1c l\u00e0 ph\u1ea7n gan \u0111\u01b0\u1ee3c gh\u00e9p \u0111\u00e3 ph\u00e1t tri\u1ec3n \u0111\u1ebfn k\u00edch th\u01b0\u1edbc b\u00ecnh th\u01b0\u1eddng khi \u0111\u1ee9a tr\u1ebb l\u1edbn l\u00ean, v\u00e0 gan c\u1ee7a ng\u01b0\u1eddi hi\u1ebfn t\u1eb7ng tr\u01b0\u1edfng th\u00e0nh c\u0169ng ph\u00e1t tri\u1ec3n tr\u1edf l\u1ea1i k\u00edch th\u01b0\u1edbc ban \u0111\u1ea7u.<\/p>\n<h2>2. T\u1eeb cha m\u1eb9 \u0111\u1ebfn con c\u00e1i<\/h2>\n<p>Ng\u01b0\u1eddi hi\u1ebfn t\u1eb7ng l\u00e0 cha m\u1eb9 c\u00f3 th\u1ec3 truy\u1ec1n m\u1ed9t ph\u1ea7n mi\u1ec5n d\u1ecbch cho con c\u00e1i, v\u00ec v\u1eady b\u1ec7nh nh\u00e2n gh\u00e9p th\u1eadn d\u01b0\u1edbi 2 tu\u1ed5i th\u01b0\u1eddng nh\u1eadn \u0111\u01b0\u1ee3c n\u1ed9i t\u1ea1ng m\u1edbi t\u1eeb cha ho\u1eb7c m\u1eb9. T\u1ea1i B\u1ec7nh vi\u1ec7n Nhi \u0111\u1ed3ng Packard, th\u1eddi gian gh\u00e9p th\u1eadn gi\u1eefa cha v\u00e0 m\u1eb9 trung b\u00ecnh k\u00e9o d\u00e0i h\u01a1n 20 n\u0103m. V\u1edbi s\u1ef1 hi\u1ec3u bi\u1ebft s\u00e2u s\u1eafc h\u01a1n v\u1ec1 c\u01a1 ch\u1ebf \u0111\u00e0o th\u1ea3i v\u00e0 s\u1ef1 ra \u0111\u1eddi c\u1ee7a c\u00e1c chi\u1ebfn l\u01b0\u1ee3c \u1ee9c ch\u1ebf mi\u1ec5n d\u1ecbch t\u1ed1t h\u01a1n, t\u1ef7 l\u1ec7 s\u1ed1ng s\u00f3t c\u1ee7a th\u1eadn d\u1ef1 ki\u1ebfn s\u1ebd t\u0103ng l\u00ean.<\/p>\n<h2>3. Kh\u00f4ng c\u1ea7n kh\u1edbp<\/h2>\n<p>Ba m\u01b0\u01a1i n\u0103m tr\u01b0\u1edbc, r\u1ea5t \u00edt b\u1ec7nh vi\u1ec7n nhi khoa th\u1ef1c hi\u1ec7n gh\u00e9p gan t\u1eeb ng\u01b0\u1eddi hi\u1ebfn t\u1eb7ng c\u00f3 nh\u00f3m m\u00e1u kh\u00f4ng tr\u00f9ng kh\u1edbp v\u1edbi tr\u1ebb. Ng\u00e0y nay, c\u00e1c b\u00e1c s\u0129 t\u1ea1i B\u1ec7nh vi\u1ec7n Nhi Packard th\u01b0\u1eddng xuy\u00ean th\u1ef1c hi\u1ec7n gh\u00e9p gan kh\u00f4ng tr\u00f9ng kh\u1edbp cho c\u1ea3 nh\u1eefng b\u1ec7nh nh\u00e2n nh\u1ecf tu\u1ed5i nh\u1ea5t. Kh\u1ea3 n\u0103ng giao thoa nh\u00f3m m\u00e1u gi\u00fap r\u00fat ng\u1eafn th\u1eddi gian ch\u1edd gh\u00e9p cho tr\u1ebb em.<\/p>\n<h2>4. Nh\u1eefng b\u1ec7nh nh\u00e2n nh\u1ecf nh\u1ea5t<\/h2>\n<p>\u1ede tr\u1ebb nh\u1ecf, c\u00e1c m\u1ea1ch m\u00e1u li\u00ean quan \u0111\u1ebfn gh\u00e9p gan v\u00e0 th\u1eadn r\u1ea5t nh\u1ecf \u0111\u1ebfn m\u1ee9c b\u00e1c s\u0129 ph\u1eabu thu\u1eadt ph\u1ea3i s\u1eed d\u1ee5ng ch\u1ec9 kh\u00e2u kh\u00f4ng th\u1ec3 nh\u00ecn th\u1ea5y b\u1eb1ng m\u1eaft th\u01b0\u1eddng. \u0110\u1ed1i v\u1edbi b\u1ec7nh nh\u00e2n nh\u1ecf tu\u1ed5i \u0111\u01b0\u1ee3c gh\u00e9p th\u1eadn ng\u01b0\u1eddi l\u1edbn, c\u00e1c b\u00e1c s\u0129 t\u1ea1i B\u1ec7nh vi\u1ec7n Nhi \u0111\u1ed3ng Packard c\u0169ng ti\u00ean phong \u00e1p d\u1ee5ng k\u1ef9 thu\u1eadt thay d\u1ecbch t\u00edch c\u1ef1c \u0111\u1ec3 t\u0103ng l\u01b0u l\u01b0\u1ee3ng m\u00e1u. B\u00ean c\u1ea1nh \u0111\u1ed9 ch\u00ednh x\u00e1c tuy\u1ec7t \u0111\u1ed1i trong ph\u1eabu thu\u1eadt, \u0111\u1ed9i ng\u0169 gh\u00e9p t\u1ea1ng c\u00f2n cung c\u1ea5p d\u1ecbch v\u1ee5 ch\u0103m s\u00f3c to\u00e0n di\u1ec7n cho tr\u1ebb em tr\u01b0\u1edbc v\u00e0 sau gh\u00e9p \u0111\u1ec3 \u0111\u1ea3m b\u1ea3o k\u1ebft qu\u1ea3 t\u1ed1t nh\u1ea5t c\u00f3 th\u1ec3. Hi\u1ec7n nay, t\u1ea1i B\u1ec7nh vi\u1ec7n Nhi \u0111\u1ed3ng Packard, t\u1ef7 l\u1ec7 s\u1ed1ng s\u00f3t c\u1ee7a b\u1ec7nh nh\u00e2n gh\u00e9p gan d\u01b0\u1edbi 2 tu\u1ed5i \u0111\u1ea1t g\u1ea7n 100%, v\u00e0 ngay c\u1ea3 tr\u1ebb s\u01a1 sinh c\u0169ng \u0111\u01b0\u1ee3c c\u1ee9u s\u1ed1ng nh\u1edd c\u00e1c ca ph\u1eabu thu\u1eadt gh\u00e9p gan.<\/p>\n<h2>5. Tr\u1ebb em \u201ckh\u00f4ng th\u1ec3 c\u1ea5y gh\u00e9p\u201d<\/h2>\n<p>Ph\u1ea3n \u1ee9ng v\u1edbi c\u00e1c ca gh\u00e9p th\u1eadn, truy\u1ec1n m\u00e1u ho\u1eb7c ti\u00eam ch\u1ee7ng tr\u01b0\u1edbc \u0111\u00f3, nhi\u1ec1u tr\u1ebb em c\u1ea7n gh\u00e9p th\u1eadn c\u00f3 h\u1ec7 mi\u1ec5n d\u1ecbch qu\u00e1 m\u1eabn c\u1ea3m, d\u1ec5 t\u1ea5n c\u00f4ng c\u00e1c c\u01a1 quan m\u1edbi. B\u1ec7nh vi\u1ec7n Nhi Packard l\u00e0 m\u1ed9t trong s\u1ed1 \u00edt b\u1ec7nh vi\u1ec7n cung c\u1ea5p d\u1ecbch v\u1ee5 ch\u0103m s\u00f3c cho tr\u1ebb em \u0111\u01b0\u1ee3c coi l\u00e0 &quot;kh\u00f4ng th\u1ec3 gh\u00e9p&quot;. M\u1ed9t ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb, l\u1ecdc huy\u1ebft t\u01b0\u01a1ng, gi\u00fap lo\u1ea1i b\u1ecf c\u00e1c kh\u00e1ng th\u1ec3 c\u00f3 kh\u1ea3 n\u0103ng t\u1ea5n c\u00f4ng th\u1eadn t\u1eeb ng\u01b0\u1eddi hi\u1ebfn t\u1eb7ng c\u00f3 nh\u00f3m m\u00e1u kh\u00e1c. C\u00e1c x\u00e9t nghi\u1ec7m trong ph\u00f2ng th\u00ed nghi\u1ec7m \u0111\u01b0\u1ee3c ph\u00e1t tri\u1ec3n t\u1ea1i Stanford c\u0169ng c\u00f3 th\u1ec3 x\u00e1c \u0111\u1ecbnh xem b\u1ec7nh nh\u00e2n c\u00f3 c\u00e1c kh\u00e1ng th\u1ec3 \u0111\u1eb7c hi\u1ec7u c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c lo\u1ea1i b\u1ecf b\u1eb1ng c\u00e1ch truy\u1ec1n t\u0129nh m\u1ea1ch immunoglobulin hay kh\u00f4ng.<\/p>\n<h2>6. Gh\u00e9p \u0111a c\u01a1 quan<\/h2>\n<p>B\u1ec7nh vi\u1ec7n Nhi Packard l\u00e0 m\u1ed9t trong s\u1ed1 \u00edt b\u1ec7nh vi\u1ec7n nhi th\u1ef1c hi\u1ec7n gh\u00e9p \u0111a t\u1ea1ng, bao g\u1ed3m gh\u00e9p gan-th\u1eadn, gh\u00e9p gan-tim, gh\u00e9p gan-ru\u1ed9t, v\u00e0 ca gh\u00e9p gan-ph\u1ed5i \u0111\u00f4i \u0111\u1ea7u ti\u00ean \u1edf tr\u1ebb em. &quot;M\u1ed9t l\u1ee3i th\u1ebf khi \u0111i\u1ec1u tr\u1ecb t\u1ea1i b\u1ec7nh vi\u1ec7n n\u00e0y l\u00e0 ch\u00fang t\u00f4i c\u00f3 r\u1ea5t nhi\u1ec1u chuy\u00ean gia gh\u00e9p t\u1ea1ng t\u1ea1i ch\u1ed7&quot;, b\u00e1c s\u0129 Esquivel n\u00f3i.<\/p>\n<h2>7. C\u00e1c ph\u01b0\u01a1ng ph\u00e1p thay th\u1ebf cho vi\u1ec7c c\u1ea5y gh\u00e9p<\/h2>\n<p>Ti\u1ebfn s\u0129 Kenneth Cox, gi\u00e1o s\u01b0 khoa ti\u00eau h\u00f3a nhi khoa, v\u00e0 c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u kh\u00e1c \u0111ang ph\u00e1t tri\u1ec3n c\u00e1c li\u1ec7u ph\u00e1p ti\u00ean ti\u1ebfn gi\u00fap ng\u0103n ng\u1eeba nhu c\u1ea7u gh\u00e9p gan. N\u0103m 1993, Cox ph\u00e1t hi\u1ec7n ra r\u1eb1ng m\u1ed9t lo\u1ea1i kh\u00e1ng sinh c\u00f3 t\u00ean l\u00e0 vancomycin kh\u00f4ng ch\u1ec9 h\u1eefu \u00edch trong vi\u1ec7c \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m tr\u00f9ng do vi khu\u1ea9n m\u00e0 c\u00f2n trong vi\u1ec7c \u0111i\u1ec1u tr\u1ecb m\u1ed9t b\u1ec7nh gan v\u00e0 \u0111\u1ea1i tr\u00e0ng hi\u1ebfm g\u1eb7p g\u1ecdi l\u00e0 vi\u00eam \u0111\u01b0\u1eddng m\u1eadt x\u01a1 c\u1ee9ng nguy\u00ean ph\u00e1t. Tr\u01b0\u1edbc \u0111\u00e2y, gh\u00e9p gan l\u00e0 c\u00e1ch duy nh\u1ea5t \u0111\u1ec3 ch\u1ed1ng l\u1ea1i c\u0103n b\u1ec7nh n\u00e0y. Ngo\u00e0i ra, nghi\u00ean c\u1ee9u sinh sau ti\u1ebfn s\u0129 Rebecca Berquist McKenzie, Ti\u1ebfn s\u0129, \u0111ang ph\u00e1t tri\u1ec3n m\u1ed9t ph\u00e1c \u0111\u1ed3 m\u1edbi \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb cho tr\u1ebb em b\u1ecb suy gan do vi\u00eam gan c\u1ea5p t\u00ednh. Cho \u0111\u1ebfn nay, ch\u00edn tr\u1ebb em b\u1ecb vi\u00eam gan do trung gian mi\u1ec5n d\u1ecbch \u0111\u00e3 \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb. H\u01a1n m\u1ed9t n\u1eeda s\u1ed1 tr\u1ebb em hi\u1ec7n \u0111\u00e3 kh\u1ecfi vi\u00eam gan v\u00e0 c\u00f3 gan ho\u1ea1t \u0111\u1ed9ng \u0111\u1ea7y \u0111\u1ee7, do \u0111\u00f3 tr\u00e1nh \u0111\u01b0\u1ee3c nhu c\u1ea7u gh\u00e9p gan.<\/p>\n<h2>8. Kh\u00f4ng c\u00f2n steroid n\u1eefa<\/h2>\n<p>Trong nhi\u1ec1u th\u1eadp k\u1ef7, tr\u1ebb em sau gh\u00e9p th\u1eadn \u0111\u01b0\u1ee3c d\u00f9ng steroid \u0111\u1ec3 ng\u0103n ng\u1eeba th\u1ea3i gh\u00e9p. Tuy nhi\u00ean, vi\u1ec7c s\u1eed d\u1ee5ng steroid k\u00e9o d\u00e0i th\u01b0\u1eddng d\u1eabn \u0111\u1ebfn c\u00e1c bi\u1ebfn ch\u1ee9ng nghi\u00eam tr\u1ecdng, ch\u1eb3ng h\u1ea1n nh\u01b0 lo\u1ea1n s\u1ea3n x\u01b0\u01a1ng h\u00f4ng, vi\u00eam kh\u1edbp, ti\u1ec3u \u0111\u01b0\u1eddng, nhi\u1ec5m tr\u00f9ng v\u00e0 nhi\u1ec1u v\u1ea5n \u0111\u1ec1 chuy\u1ec3n h\u00f3a kh\u00e1c. V\u00e0o nh\u1eefng n\u0103m 1990, c\u00e1c b\u00e1c s\u0129 t\u1ea1i B\u1ec7nh vi\u1ec7n Nhi Packard \u0111\u00e3 m\u1ea1nh d\u1ea1n ng\u1eebng \u0111i\u1ec1u tr\u1ecb steroid cho b\u1ec7nh nh\u00e2n sau gh\u00e9p. V\u00e0o th\u1eddi \u0111i\u1ec3m \u0111\u00f3, \u00fd t\u01b0\u1edfng n\u00e0y \u0111\u01b0\u1ee3c coi l\u00e0 c\u00f3 nguy c\u01a1 cao, nh\u01b0ng t\u1ef7 l\u1ec7 th\u1ea3i gh\u00e9p \u0111\u00e3 \u0111\u01b0\u1ee3c ch\u1ee9ng minh l\u00e0 th\u1ea5p, v\u00e0 b\u1ec7nh nh\u00e2n kh\u00f4ng ph\u1ea3i ch\u1ecbu t\u00e1c d\u1ee5ng ph\u1ee5 c\u1ee7a steroid. Ng\u00e0y nay, ph\u00e1c \u0111\u1ed3 kh\u00f4ng steroid \u0111ang tr\u1edf th\u00e0nh ti\u00eau chu\u1ea9n ch\u0103m s\u00f3c cho c\u00e1c ca gh\u00e9p th\u1eadn nhi khoa tr\u00ean to\u00e0n th\u1ebf gi\u1edbi.<\/p>\n<h2>9. Ch\u1ed1ng l\u1ea1i vi-r\u00fat ch\u1ebft ng\u01b0\u1eddi<\/h2>\n<p>Qu\u00e1 li\u1ec1u thu\u1ed1c \u1ee9c ch\u1ebf mi\u1ec5n d\u1ecbch c\u00f3 th\u1ec3 g\u00e2y ra c\u00e1c b\u1ec7nh nhi\u1ec5m tr\u00f9ng nguy hi\u1ec3m nh\u01b0 virus Epstein-Barr, c\u00f3 th\u1ec3 g\u00e2y ung th\u01b0 b\u1ea1ch c\u1ea7u, ho\u1eb7c virus BK, g\u00e2y h\u1ee7y ho\u1ea1i th\u1eadn gh\u00e9p. V\u1edbi s\u1ef1 h\u1ed7 tr\u1ee3 t\u1eeb Vi\u1ec7n Y t\u1ebf Qu\u1ed1c gia v\u00e0 c\u00e1c nh\u00e0 t\u00e0i tr\u1ee3 t\u01b0 nh\u00e2n, c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u \u0111ang n\u1ed7 l\u1ef1c t\u00ecm hi\u1ec3u s\u00e2u h\u01a1n v\u1ec1 virus, x\u00e1c \u0111\u1ecbnh nh\u1eefng b\u1ec7nh nh\u00e2n c\u00f3 nguy c\u01a1 cao v\u00e0 lo\u1ea1i b\u1ecf nguy c\u01a1 m\u1eafc c\u00e1c b\u1ec7nh nhi\u1ec5m tr\u00f9ng nguy hi\u1ec3m n\u00e0y.<\/p>\n<h2>10. Li\u1ec7u ph\u00e1p t\u1ebf b\u00e0o g\u1ed1c<\/h2>\n<p>M\u1ed9t ng\u00e0y n\u00e0o \u0111\u00f3, t\u1ebf b\u00e0o g\u1ed1c gan c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng thay th\u1ebf cho gh\u00e9p gan. M\u1eb7c d\u00f9 c\u00f2n nhi\u1ec1u tham v\u1ecdng, nh\u01b0ng m\u1ee5c ti\u00eau l\u00e0 s\u1eed d\u1ee5ng d\u1ecbch truy\u1ec1n t\u1ebf b\u00e0o g\u1ed1c gan nh\u01b0 m\u1ed9t li\u1ec7u ph\u00e1p h\u1ed7 tr\u1ee3 cho tr\u1ebb em b\u1ecb vi\u00eam gan t\u1ed1i c\u1ea5p cho \u0111\u1ebfn khi gan c\u1ee7a c\u00e1c em h\u1ed3i ph\u1ee5c, ho\u1eb7c nh\u01b0 m\u1ed9t c\u1ea7u n\u1ed1i tr\u01b0\u1edbc khi gh\u00e9p gan. \u1ede tr\u1ebb em m\u1eafc c\u00e1c r\u1ed1i lo\u1ea1n chuy\u1ec3n h\u00f3a khi\u1ebfn gan s\u1ea3n xu\u1ea5t \u0111\u1ed9c t\u1ed1 g\u00e2y t\u1ed5n th\u01b0\u01a1ng n\u00e3o, li\u1ec7u ph\u00e1p t\u1ebf b\u00e0o g\u1ed1c c\u00f3 th\u1ec3 l\u00e0 m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb hi\u1ec7u qu\u1ea3 v\u00e0 \u00edt x\u00e2m l\u1ea5n h\u01a1n so v\u1edbi vi\u1ec7c thay th\u1ebf to\u00e0n b\u1ed9 gan. &quot;Hi\u1ec7n t\u1ea1i, n\u1ebfu m\u1ed9t gen b\u1ecb khi\u1ebfm khuy\u1ebft, ch\u00fang t\u00f4i ph\u1ea3i thay th\u1ebf to\u00e0n b\u1ed9 gan&quot;, Esquivel n\u00f3i. &quot;\u0110\u1ed1i v\u1edbi nh\u1eefng tr\u1ebb em c\u1ea7n gh\u00e9p gan, \u0111\u1ed9i ng\u0169 c\u1ee7a ch\u00fang t\u00f4i \u0111\u00e3 s\u1eb5n s\u00e0ng. Nh\u01b0ng \u0111\u1ed3ng th\u1eddi, ch\u00fang t\u00f4i c\u0169ng cam k\u1ebft t\u00ecm ra c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb gi\u00fap b\u1ec7nh nh\u00e2n tr\u00e1nh \u0111\u01b0\u1ee3c vi\u1ec7c gh\u00e9p gan n\u1ebfu c\u00f3 th\u1ec3.&quot;<\/p>\n<p><em>B\u00e0i vi\u1ebft n\u00e0y xu\u1ea5t hi\u1ec7n tr\u00ean \u1ea5n ph\u1ea9m Lucile Packard Children&#039;s News v\u00e0o m\u00f9a thu n\u0103m 2013.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>1. C\u00e1c c\u01a1 quan l\u1edbn d\u00e0nh cho tr\u1ebb nh\u1ecf \u201cDo t\u00ecnh tr\u1ea1ng thi\u1ebfu h\u1ee5t n\u1ed9i t\u1ea1ng tr\u1ea7m tr\u1ecdng \u1edf tr\u1ebb em n\u00ean ch\u00fang t\u00f4i ph\u1ea3i s\u00e1ng t\u1ea1o\u201d, Ti\u1ebfn s\u0129, B\u00e1c s\u0129 Carlos Esquivel cho bi\u1ebft\u2026.<\/p>","protected":false},"author":17,"featured_media":3527,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"categories":[148,22],"class_list":["post-3526","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-in-the-news","category-patient-stories","health_topic-transplant"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.3 (Yoast SEO v27.3) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Expanding the Realm of Possibility: 10 Breakthroughs in Pediatric Organ Transplantation   Pioneered at Lucile Packard Children\u2019s Hospital - Lucile Packard Foundation for Children&#039;s Health<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"http:\/\/lpfch.org\/vi\/impact-stories\/expanding-the-realm-of-possibility-10-breakthroughs-in-pediatric-organ-transplantation-pioneered-at-lucile-packard-childrens-hospital\/\" \/>\n<meta property=\"og:locale\" content=\"vi_VN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Expanding the Realm of Possibility: 10 Breakthroughs in Pediatric Organ Transplantation   Pioneered at Lucile Packard Children\u2019s Hospital\" \/>\n<meta property=\"og:description\" content=\"1. Big Organs for Little Kids \u201cBecause of the chronic shortage of organs for children, we\u2019ve had to get creative,\u201d says Carlos Esquivel, MD, PhD....\" \/>\n<meta property=\"og:url\" content=\"http:\/\/lpfch.org\/vi\/impact-stories\/expanding-the-realm-of-possibility-10-breakthroughs-in-pediatric-organ-transplantation-pioneered-at-lucile-packard-childrens-hospital\/\" \/>\n<meta property=\"og:site_name\" content=\"Lucile Packard Foundation for Children&#039;s Health\" \/>\n<meta property=\"article:published_time\" content=\"2014-08-20T23:27:52+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-09-13T18:27:35+00:00\" \/>\n<meta property=\"og:image\" content=\"http:\/\/lpfch.org\/wp-content\/uploads\/2024\/01\/expandingrealmpossibilities1-scaled.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"2560\" \/>\n\t<meta property=\"og:image:height\" content=\"1374\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"admin\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"admin\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"5 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"http:\\\/\\\/lpfch.org\\\/km\\\/impact-stories\\\/expanding-the-realm-of-possibility-10-breakthroughs-in-pediatric-organ-transplantation-pioneered-at-lucile-packard-childrens-hospital\\\/#article\",\"isPartOf\":{\"@id\":\"http:\\\/\\\/lpfch.org\\\/km\\\/impact-stories\\\/expanding-the-realm-of-possibility-10-breakthroughs-in-pediatric-organ-transplantation-pioneered-at-lucile-packard-childrens-hospital\\\/\"},\"author\":{\"name\":\"admin\",\"@id\":\"https:\\\/\\\/lpfch.org\\\/vi\\\/#\\\/schema\\\/person\\\/0c27ee3a03f60d4845413e6163db996c\"},\"headline\":\"Expanding the Realm of Possibility: 10 Breakthroughs in Pediatric Organ Transplantation Pioneered at Lucile Packard Children\u2019s Hospital\",\"datePublished\":\"2014-08-20T23:27:52+00:00\",\"dateModified\":\"2024-09-13T18:27:35+00:00\",\"mainEntityOfPage\":{\"@id\":\"http:\\\/\\\/lpfch.org\\\/km\\\/impact-stories\\\/expanding-the-realm-of-possibility-10-breakthroughs-in-pediatric-organ-transplantation-pioneered-at-lucile-packard-childrens-hospital\\\/\"},\"wordCount\":897,\"commentCount\":0,\"image\":{\"@id\":\"http:\\\/\\\/lpfch.org\\\/km\\\/impact-stories\\\/expanding-the-realm-of-possibility-10-breakthroughs-in-pediatric-organ-transplantation-pioneered-at-lucile-packard-childrens-hospital\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/lpfch.org\\\/wp-content\\\/uploads\\\/2024\\\/01\\\/expandingrealmpossibilities1-scaled.jpg\",\"articleSection\":[\"In the News\",\"Patient Stories\"],\"inLanguage\":\"vi\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"http:\\\/\\\/lpfch.org\\\/km\\\/impact-stories\\\/expanding-the-realm-of-possibility-10-breakthroughs-in-pediatric-organ-transplantation-pioneered-at-lucile-packard-childrens-hospital\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"http:\\\/\\\/lpfch.org\\\/km\\\/impact-stories\\\/expanding-the-realm-of-possibility-10-breakthroughs-in-pediatric-organ-transplantation-pioneered-at-lucile-packard-childrens-hospital\\\/\",\"url\":\"http:\\\/\\\/lpfch.org\\\/km\\\/impact-stories\\\/expanding-the-realm-of-possibility-10-breakthroughs-in-pediatric-organ-transplantation-pioneered-at-lucile-packard-childrens-hospital\\\/\",\"name\":\"Expanding the Realm of Possibility: 10 Breakthroughs in Pediatric Organ Transplantation Pioneered at Lucile Packard Children\u2019s Hospital - 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