{"id":3598,"date":"2014-08-28T21:19:25","date_gmt":"2014-08-28T21:19:25","guid":{"rendered":"https:\/\/lpfch.org\/return-on-investment-tench-palo-alto\/"},"modified":"2024-02-14T14:06:50","modified_gmt":"2024-02-14T14:06:50","slug":"return-on-investment-tench-palo-alto","status":"publish","type":"post","link":"https:\/\/lpfch.org\/vi\/impact-stories\/return-on-investment-tench-palo-alto\/","title":{"rendered":"L\u1ee3i t\u1ee9c \u0111\u1ea7u t\u01b0: Tench, Palo Alto"},"content":{"rendered":"

Li\u1ec7u ph\u00e1p nh\u1eafm tr\u00fang \u0111\u00edch \u0111\u00e3 tr\u1edf th\u00e0nh m\u1ed9t m\u1ee5c ti\u00eau t\u1ed1i th\u01b0\u1ee3ng trong y h\u1ecdc nhi khoa. M\u1ee5c ti\u00eau l\u00e0 thi\u1ebft k\u1ebf c\u00e1c lo\u1ea1i thu\u1ed1c m\u1edbi nh\u1eafm v\u00e0o c\u00e1c ph\u00e2n t\u1eed v\u00e0 gen c\u1ee5 th\u1ec3 g\u00e2y ra b\u1ec7nh \u1edf tr\u1ebb em. Thu\u1ed1c nh\u1eafm tr\u00fang \u0111\u00edch \u0111\u00e3 \u0111\u01b0\u1ee3c ch\u1ee9ng minh l\u00e0 hi\u1ec7u qu\u1ea3 h\u01a1n x\u1ea1 tr\u1ecb ho\u1eb7c h\u00f3a tr\u1ecb trong \u0111i\u1ec1u tr\u1ecb m\u1ed9t s\u1ed1 lo\u1ea1i ung th\u01b0, \u0111\u1ed3ng th\u1eddi \u00edt t\u00e1c d\u1ee5ng ph\u1ee5 g\u00e2y suy nh\u01b0\u1ee3c h\u01a1n, ch\u1eb3ng h\u1ea1n nh\u01b0 bu\u1ed3n n\u00f4n, s\u1ee5t c\u00e2n v\u00e0 m\u1ec7t m\u1ecfi.<\/p>\n

T\u1ea1i Tr\u01b0\u1eddng Y khoa \u0110\u1ea1i h\u1ecdc Stanford, Ti\u1ebfn s\u0129 Michael Cleary, Gi\u00e1m \u0111\u1ed1c B\u1ed9 m\u00f4n Sinh h\u1ecdc Ung th\u01b0 Nhi khoa, \u0111ang ti\u1ebfn h\u00e0nh nghi\u00ean c\u1ee9u ti\u00ean phong c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn c\u00e1c li\u1ec7u ph\u00e1p nh\u1eafm m\u1ee5c ti\u00eau cho b\u1ec7nh b\u1ea1ch c\u1ea7u, u lympho v\u00e0 c\u00e1c lo\u1ea1i ung th\u01b0 kh\u00e1c \u1edf tr\u1ebb em. Tuy nhi\u00ean, \u0111\u1ed1i v\u1edbi Cleary v\u00e0 c\u00e1c nh\u00e0 khoa h\u1ecdc kh\u00e1c, vi\u1ec7c \u0111\u1ea3m b\u1ea3o h\u1ed7 tr\u1ee3 t\u00e0i ch\u00ednh cho nghi\u00ean c\u1ee9u c\u01a1 b\u1ea3n v\u1ec1 ung th\u01b0 nhi khoa lu\u00f4n l\u00e0 m\u1ed9t th\u00e1ch th\u1ee9c.<\/p>\n

\u201cT\u01b0\u01a1ng \u0111\u1ed1i \u00edt tr\u1ebb em \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n m\u1eafc ung th\u01b0,\u201d Cleary, Gi\u00e1o s\u01b0 Sinh h\u1ecdc Ung th\u01b0 Nhi khoa v\u00e0 Gi\u00e1o s\u01b0 B\u1ec7nh h\u1ecdc c\u1ee7a Gia \u0111\u00ecnh Lindhard, cho bi\u1ebft. \u201cVi\u1ec7c m\u1ed9t c\u00f4ng ty d\u01b0\u1ee3c ph\u1ea9m l\u1edbn \u0111\u1ea7u t\u01b0 l\u1edbn cho m\u1ed9t s\u1ed1 \u00edt tr\u01b0\u1eddng h\u1ee3p l\u00e0 kh\u00f4ng h\u1ee3p l\u00fd v\u1ec1 m\u1eb7t t\u00e0i ch\u00ednh. V\u00ec v\u1eady, c\u00e1c t\u1ed5 ch\u1ee9c h\u1ecdc thu\u1eadt c\u1ea7n th\u1ef1c hi\u1ec7n nghi\u00ean c\u1ee9u c\u01a1 b\u1ea3n \u0111\u1ec3 t\u1ea1o ra c\u00e1c li\u1ec7u ph\u00e1p m\u1edbi cho tr\u1ebb em.\u201d<\/p>\n

\u0110\u1ed1i v\u1edbi h\u00e0ng ng\u00e0n gia \u0111\u00ecnh c\u00f3 cu\u1ed9c s\u1ed1ng b\u1ecb \u0111\u1ea3o l\u1ed9n v\u00ec ung th\u01b0, m\u1ed7i \u0111\u00f4 la d\u00e0nh cho nghi\u00ean c\u1ee9u c\u01a1 b\u1ea3n \u0111\u1ec1u l\u00e0 m\u1ed9t kho\u1ea3n chi ti\u00eau x\u1ee9ng \u0111\u00e1ng. C\u1ee9 h\u1ecfi Simone v\u00e0 Tench Coxe \u1edf Palo Alto th\u00ec bi\u1ebft. N\u0103m 2003, v\u1ee3 ch\u1ed3ng Cox \u0111\u00e3 \u0111\u01b0a c\u1eadu con trai 6 tu\u1ed5i, c\u0169ng t\u00ean l\u00e0 Tench, \u0111\u1ebfn B\u1ec7nh vi\u1ec7n Nhi \u0111\u1ed3ng Lucile Packard v\u00ec \u0111au b\u1ee5ng d\u1eef d\u1ed9i v\u00e0 s\u01b0ng h\u1ea1ch b\u1ea1ch huy\u1ebft \u1edf c\u1ed5.<\/p>\n

C\u00e1c x\u00e9t nghi\u1ec7m cho th\u1ea5y Tench b\u1ecb u lympho Burkitt, m\u1ed9t lo\u1ea1i ung th\u01b0 h\u1ec7 b\u1ea1ch huy\u1ebft. N\u1ebfu \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb s\u1edbm, tr\u1ebb em m\u1eafc Burkitt c\u00f3 t\u1ef7 l\u1ec7 s\u1ed1ng s\u00f3t l\u00ean \u0111\u1ebfn 85%. V\u00e0i ng\u00e0y sau khi \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n, c\u1eadu b\u00e9 \u0111\u00e3 tr\u1ea3i qua \u0111\u1ee3t h\u00f3a tr\u1ecb \u0111\u1ea7u ti\u00ean trong b\u1ed1n \u0111\u1ee3t t\u1ea1i Packard.<\/p>\n

Ch\u1ebf \u0111\u1ed9 \u0111i\u1ec1u tr\u1ecb b\u1ed1n th\u00e1ng n\u00e0y th\u1eadt kh\u00f3 kh\u0103n \u0111\u1ed1i v\u1edbi gia \u0111\u00ecnh Coxe. \u201cTrong su\u1ed1t 25, 30 \u0111\u00eam, ch\u00fang t\u00f4i thay phi\u00ean nhau ng\u1ee7 t\u1ea1i B\u1ec7nh vi\u1ec7n,\u201d Simone nh\u1edb l\u1ea1i. \u201c\u0110\u00f3 l\u00e0 m\u1ed9t t\u00ecnh hu\u1ed1ng kh\u00f3 kh\u0103n cho c\u00e1c gia \u0111\u00ecnh \u1edf \u0111\u00f3, nh\u01b0ng \u0111\u1ed9i ng\u0169 nh\u00e2n vi\u00ean \u1edf \u0111\u00f3 th\u00ec th\u1eadt \u0111\u00e1ng kinh ng\u1ea1c. H\u1ecd th\u1ef1c s\u1ef1 t\u1ea1o n\u00ean s\u1ef1 kh\u00e1c bi\u1ec7t.\u201d<\/p>\n

H\u00f3a tr\u1ecb \u0111\u00e3 th\u00e0nh c\u00f4ng, v\u00e0 hi\u1ec7n t\u1ea1i, Tench \u0111\u00e3 kh\u1ecfi ung th\u01b0. C\u1eadu b\u00e9 \u0111ang h\u1ecdc l\u1edbp b\u1ea3y v\u00e0 th\u00edch ch\u01a1i b\u00f3ng r\u1ed5, b\u00f3ng \u0111\u00e1, v\u00e0 \u0111\u1ecdc v\u1ec1 l\u1ecbch s\u1eed Hy L\u1ea1p v\u00e0 La M\u00e3 c\u1ed5 \u0111\u1ea1i.<\/p>\n

\u201cCh\u00fang t\u00f4i th\u1eadt may m\u1eafn khi \u0111\u01b0\u1ee3c s\u1ed1ng g\u1ea7n m\u1ed9t b\u1ec7nh vi\u1ec7n \u0111\u1eb3ng c\u1ea5p th\u1ebf gi\u1edbi nh\u01b0 v\u1eady,\u201d cha anh n\u00f3i. \u201cNh\u01b0ng '\u0111\u1eb3ng c\u1ea5p th\u1ebf gi\u1edbi' kh\u00f4ng ph\u1ea3i t\u1ef1 nhi\u00ean m\u00e0 c\u00f3. Simone v\u00e0 t\u00f4i t\u1eebng coi s\u1ee9c kh\u1ecfe l\u00e0 \u0111i\u1ec1u hi\u1ec3n nhi\u00ean. R\u1ed3i ch\u00fang t\u00f4i nh\u1eadn ra, tr\u1eddi \u01a1i, chuy\u1ec7n n\u00e0y c\u00f3 th\u1ec3 x\u1ea3y ra v\u1edbi b\u1ea5t k\u1ef3 \u0111\u1ee9a con n\u00e0o v\u00e0o b\u1ea5t k\u1ef3 l\u00fac n\u00e0o. \u0110\u00f3 l\u00e0 l\u00fac ch\u00fang t\u00f4i quy\u1ebft \u0111\u1ecbnh th\u1ef1c s\u1ef1 mu\u1ed1n h\u1ed7 tr\u1ee3 nghi\u00ean c\u1ee9u ung th\u01b0 nhi khoa.\u201d<\/p>\n

T\u1eeb n\u0103m 2004, gia \u0111\u00ecnh Coxe \u0111\u00e3 h\u1ed7 tr\u1ee3 c\u00f4ng vi\u1ec7c c\u1ee7a Cleary v\u00e0 Khoa Sinh h\u1ecdc Ung th\u01b0 Nhi khoa. "Nh\u1edd s\u1ef1 \u0111\u00f3ng g\u00f3p c\u1ee7a h\u1ecd, ch\u00fang t\u00f4i \u0111\u00e3 c\u00f3 th\u1ec3 tuy\u1ec3n th\u00eam c\u00e1c nghi\u00ean c\u1ee9u sinh sau ti\u1ebfn s\u0129 v\u00e0o ph\u00f2ng th\u00ed nghi\u1ec7m c\u1ee7a m\u00ecnh \u0111\u1ec3 th\u1ef1c hi\u1ec7n c\u00e1c th\u00ed nghi\u1ec7m s\u00e1ng t\u1ea1o m\u00e0 n\u1ebfu kh\u00f4ng s\u1ebd r\u1ea5t kh\u00f3 xin \u0111\u01b0\u1ee3c t\u00e0i tr\u1ee3", Cleary n\u00f3i.<\/p>\n

L\u00f2ng h\u1ea3o t\u00e2m c\u1ee7a v\u1ee3 ch\u1ed3ng Cox \u0111\u00e3 d\u1eabn \u0111\u1ebfn m\u1ed9t k\u1ebft qu\u1ea3 quan tr\u1ecdng. M\u1ed9t nghi\u00ean c\u1ee9u sinh sau ti\u1ebfn s\u0129 t\u1ea1i ph\u00f2ng th\u00ed nghi\u1ec7m c\u1ee7a Cleary g\u1ea7n \u0111\u00e2y \u0111\u00e3 ph\u00e1t hi\u1ec7n ra r\u1eb1ng c\u00f3 t\u1edbi 10% s\u1ed1 ca ung th\u01b0 m\u00e1u \u1edf tr\u1ebb em ph\u1ee5 thu\u1ed9c v\u00e0o m\u1ed9t lo\u1ea1i enzyme li\u00ean quan \u0111\u1ebfn b\u1ec7nh Alzheimer v\u00e0 ti\u1ec3u \u0111\u01b0\u1eddng, nh\u1eefng c\u0103n b\u1ec7nh \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn h\u00e0ng tri\u1ec7u ng\u01b0\u1eddi tr\u00ean to\u00e0n th\u1ebf gi\u1edbi. Cleary cho bi\u1ebft \u0111\u00e2y l\u00e0 m\u1ed9t kh\u00e1m ph\u00e1 c\u00f3 kh\u1ea3 n\u0103ng thu h\u00fat s\u1ef1 ch\u00fa \u00fd c\u1ee7a ng\u00e0nh c\u00f4ng nghi\u1ec7p d\u01b0\u1ee3c ph\u1ea9m.<\/p>\n

\u00d4ng n\u00f3i th\u00eam: \u201cT\u00f4i \u0111\u00e3 g\u1eb7p v\u1ee3 ch\u1ed3ng Cox v\u00e0 t\u00f4i kh\u00e1 \u1ea5n t\u01b0\u1ee3ng v\u1edbi s\u1ef1 hi\u1ec3u bi\u1ebft c\u1ee7a h\u1ecd v\u1ec1 nhu c\u1ea7u h\u1ed7 tr\u1ee3 nghi\u00ean c\u1ee9u h\u1ecdc thu\u1eadt c\u01a1 b\u1ea3n nh\u01b0 m\u1ed9t n\u1ec1n t\u1ea3ng cho c\u00e1c li\u1ec7u ph\u00e1p nhi khoa m\u1edbi\u201d.<\/p>\n

N\u0103m 2010, Tench v\u00e0 Simone \u0111\u00e3 t\u0103ng c\u01b0\u1eddng s\u1ef1 h\u1ed7 tr\u1ee3 tr\u01b0\u1edbc \u0111\u00f3 c\u1ee7a h\u1ecd b\u1eb1ng cam k\u1ebft l\u1edbn gi\u00fap t\u00e0i tr\u1ee3 cho d\u1ef1 \u00e1n m\u1edf r\u1ed9ng B\u1ec7nh vi\u1ec7n nhi Packard.<\/p>\n

\u201cY h\u1ecdc s\u1ebd \u0111\u01b0\u1ee3c c\u1ea3i thi\u1ec7n khi m\u1ecdi ng\u01b0\u1eddi \u0111\u1ea7u t\u01b0 v\u00e0o n\u00f3,\u201d Simone n\u00f3i. \u201cCh\u00fang t\u00f4i \u0111\u00e3 \u0111\u01b0\u1ee3c h\u01b0\u1edfng l\u1ee3i t\u1eeb bao nhi\u00eau n\u0103m nghi\u00ean c\u1ee9u v\u1ec1 b\u1ec7nh u lympho. Nh\u00ecn v\u1ec1 t\u01b0\u01a1ng lai, ch\u00fang t\u00f4i mu\u1ed1n B\u1ec7nh vi\u1ec7n Nhi Packard tr\u1edf th\u00e0nh b\u1ec7nh vi\u1ec7n t\u1ed1t nh\u1ea5t v\u1ec1 m\u1ecdi m\u1eb7t, kh\u00f4ng ch\u1ec9 ri\u00eang ch\u0103m s\u00f3c ung th\u01b0. B\u1ec7nh vi\u1ec7n ph\u1ee5c v\u1ee5 c\u1ed9ng \u0111\u1ed3ng r\u1ea5t t\u1ed1t, v\u00e0 ch\u00fang t\u00f4i l\u00e0 m\u1ed9t ph\u1ea7n c\u1ee7a c\u1ed9ng \u0111\u1ed3ng n\u00e0y.\u201d<\/p>","protected":false},"excerpt":{"rendered":"

Li\u1ec7u ph\u00e1p nh\u1eafm m\u1ee5c ti\u00eau \u0111\u00e3 tr\u1edf th\u00e0nh m\u1ed9t m\u1ee5c ti\u00eau t\u1ed1i th\u01b0\u1ee3ng trong y h\u1ecdc nhi khoa. M\u1ee5c ti\u00eau l\u00e0 thi\u1ebft k\u1ebf c\u00e1c lo\u1ea1i thu\u1ed1c m\u1edbi nh\u1eafm v\u00e0o c\u00e1c ph\u00e2n t\u1eed v\u00e0 gen c\u1ee5 th\u1ec3 g\u00e2y ra\u2026<\/p>","protected":false},"author":17,"featured_media":3599,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"categories":[148,22],"class_list":["post-3598","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-in-the-news","category-patient-stories"],"acf":[],"yoast_head":"\nReturn on Investment: Tench, Palo Alto - Lucile Packard Foundation for Children's Health<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"http:\/\/lpfch.org\/vi\/impact-stories\/return-on-investment-tench-palo-alto\/\" \/>\n<meta property=\"og:locale\" content=\"vi_VN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Return on Investment: Tench, Palo Alto\" \/>\n<meta property=\"og:description\" content=\"Targeted therapy has become a holy grail in pediatric medicine. 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