{"id":4307,"date":"2022-11-09T01:01:43","date_gmt":"2022-11-09T01:01:43","guid":{"rendered":"https:\/\/lpfch.org\/unraveling-the-mysteries-of-22q11-2-deletion-syndrome\/"},"modified":"2024-11-22T20:21:29","modified_gmt":"2024-11-22T20:21:29","slug":"unraveling-the-mysteries-of-22q11-2-deletion-syndrome","status":"publish","type":"post","link":"https:\/\/lpfch.org\/zh\/impact-stories\/unraveling-the-mysteries-of-22q11-2-deletion-syndrome\/","title":{"rendered":"\u63ed\u5f0022q11.2\u7f3a\u5931\u7efc\u5408\u5f81\u7684\u5965\u79d8"},"content":{"rendered":"

\u9664\u975e\u60a8\u7684\u5bb6\u65cf\u60a3\u670922q11.2\u7f3a\u5931\u7efc\u5408\u5f81\uff0822q11.2DS\uff09\uff0c\u5426\u5219\u60a8\u53ef\u80fd\u4ece\u672a\u542c\u8bf4\u8fc7\u8fd9\u79cd\u75be\u75c5\u3002\u636e\u4f30\u8ba1\uff0c\u6bcf2000\u81f34000\u540d\u5a74\u513f\u4e2d\u5c31\u6709\u4e00\u540d\u60a3\u6709\u8fd9\u79cd\u9057\u4f20\u6027\u75be\u75c5\u3002\u867d\u7136\u542c\u8d77\u6765\u5f88\u7f55\u89c1\uff0c\u4f46\u5b83\u4f1a\u5f71\u54cd\u8eab\u4f53\u7684\u591a\u4e2a\u90e8\u4f4d\uff0c\u5e76\u53ef\u80fd\u5bfc\u81f4\u816d\u88c2\u3001\u5fc3\u810f\u7f3a\u9677\u3001\u514d\u75ab\u7cfb\u7edf\u529f\u80fd\u4f4e\u4e0b\u3001\u8033\u90e8\u611f\u67d3\u6216\u542c\u529b\u4e27\u5931\u3001\u766b\u75eb\u3001\u81ea\u95ed\u75c7\u3001\u884c\u4e3a\u548c\u60c5\u7eea\u95ee\u9898\uff0c\u4ee5\u53ca\u5176\u4ed6\u4e25\u91cd\u5f71\u54cd\u513f\u7ae5\u5065\u5eb7\u548c\u751f\u6d3b\u8d28\u91cf\u7684\u75be\u75c5\u3002<\/p>\n

\u60a3\u670922q11.2\u7f3a\u5931\u7efc\u5408\u5f81\u7684\u513f\u7ae5\uff0c\u517622\u53f7\u67d3\u8272\u4f53\u4e0a\u7f3a\u5931\u4e86\u4e00\u5c0f\u6bb5\uff0c\u7f3a\u5931\u4f4d\u7f6e\u4f4d\u4e8e\u67d3\u8272\u4f53\u4e2d\u95f4\u7684q11.2\u533a\u57df\u3002\u8fd9\u79cd\u590d\u6742\u7684\u75be\u75c5\u5bf9\u6bcf\u4e2a\u5b69\u5b50\u7684\u5f71\u54cd\u5404\u4e0d\u76f8\u540c\uff0c\u75c7\u72b6\u8f7b\u91cd\u4e0d\u4e00\uff0c\u4ece\u8f7b\u5fae\u75c7\u72b6\u5230\u4e25\u91cd\u7684\u5065\u5eb7\u95ee\u9898\u90fd\u6709\u53ef\u80fd\u3002\u5230\u4e86\u9752\u6625\u671f\u548c\u6210\u5e74\u671f\uff0c\u4e3b\u8981\u7684\u6311\u6218\u5728\u4e8e\u5927\u8111\u5065\u5eb7\u2014\u2014\u793e\u4ea4\u7126\u8651\u3001\u5b66\u4e60\u56f0\u96be\uff0c\u6709\u65f6\u8fd8\u4f1a\u51fa\u73b0\u66f4\u4e25\u91cd\u7684\u7cbe\u795e\u969c\u788d\u3002<\/p>\n

\u867d\u7136\u76ee\u524d\u5c1a\u65e0\u6cbb\u6108\u65b9\u6cd5\uff0c\u4f46\u5982\u679c\u5fc3\u810f\u75c5\u4e13\u5bb6\u3001\u6574\u5f62\u5916\u79d1\u533b\u751f\u3001\u514d\u75ab\u5b66\u5bb6\u3001\u795e\u7ecf\u79d1\u533b\u751f\u3001\u8bed\u8a00\u548c\u7269\u7406\u6cbb\u7597\u5e08\u4ee5\u53ca\u884c\u4e3a\u4e13\u5bb6\u7b49\u4e13\u5bb6\u80fd\u591f\u5171\u540c\u63d0\u4f9b\u5168\u9762\u7684\u62a4\u7406\uff0c\u5e76\u5bf9\u60a3\u6709 22q11.2DS \u7684\u513f\u7ae5\u8fdb\u884c\u65e9\u671f\u6709\u6548\u7684\u5e72\u9884\uff0c\u5927\u591a\u6570\u513f\u7ae5\u90fd\u80fd\u8fc7\u4e0a\u957f\u5bff\u3001\u5065\u5eb7\u3001\u79ef\u6781\u7684\u751f\u6d3b\u3002<\/p>\n

\u73b0\u5728\uff0c\u5f97\u76ca\u4e8e\u6148\u5584\u6350\u52a9\uff0c\u65af\u5766\u798f\u5927\u5b66\u533b\u5b66\u9662\u548c\u65af\u5766\u798f\u5362\u897f\u5c14\u00b7\u5e15\u5361\u5fb7\u513f\u7ae5\u533b\u9662\u7684\u533b\u751f\u548c\u79d1\u5b66\u5bb6\u4eec\u5728\u4e86\u89e3\u8be5\u75be\u75c5\u7684\u6f5c\u5728\u673a\u5236\u548c\u6539\u8fdb\u5176\u5404\u79cd\u75c7\u72b6\u7684\u6cbb\u7597\u65b9\u6cd5\u65b9\u9762\u53d6\u5f97\u4e86\u7a81\u7834\u6027\u53d1\u73b0\u3002<\/p>\n

\u7814\u7a76\u4eba\u5458\u63ed\u793a\u8111\u7ec6\u80de\u53d1\u80b2\u7684\u7ebf\u7d22<\/h3>\n

\u574e\u8fea\u65af\u00b7\u4e4c\u4f0a\u6ed5\u82cf\u00b7\u6c49\u5bc6\u5c14\u987f (Candice Uytengsu Hamilton) \u957f\u671f\u4ee5\u6765\u4e00\u76f4\u662f\u5e15\u5361\u5fb7\u513f\u7ae5\u533b\u9662\u7684\u652f\u6301\u8005\uff0c\u5979\u6df1\u77e5\u652f\u6301\u795e\u7ecf\u7cbe\u795e\u75be\u75c5\u6311\u6218\u7684\u5fc5\u8981\u6027\uff0c\u5c24\u5176\u662f\u9488\u5bf9 22q11.2 \u7f3a\u5931\u7efc\u5408\u5f81 (22q11.2DS) \u60a3\u8005\u3002\u5979\u521b\u7acb\u7684\u4e4c\u4f0a\u6ed5\u82cf-\u6c49\u5bc6\u5c14\u987f 22q11 \u795e\u7ecf\u7cbe\u795e\u75c5\u5b66\u7814\u7a76\u9879\u76ee\u96b6\u5c5e\u4e8e\u65af\u5766\u798f\u6bcd\u5a74\u5065\u5eb7\u7814\u7a76\u6240 (MCHRI)\uff0c\u76ee\u524d\u6b63\u81f4\u529b\u4e8e\u4e3a 22q11.2DS \u60a3\u513f\u63a2\u7d22\u4ee4\u4eba\u632f\u594b\u7684\u5168\u65b0\u7814\u7a76\u65b9\u5411\u3002<\/p>\n

\u8be5\u9879\u76ee\u8d44\u52a9\u65e8\u5728\u6539\u558422q11.2\u7f3a\u5931\u7efc\u5408\u5f81\u60a3\u513f\u795e\u7ecf\u8ba4\u77e5\u529f\u80fd\u7684\u7814\u7a76\u3002\u8fd9\u7c7b\u60a3\u513f\u7f79\u60a3\u7126\u8651\u75c7\u3001\u81ea\u95ed\u75c7\u3001\u6ce8\u610f\u529b\u7f3a\u9677\u969c\u788d\u4ee5\u53ca\u884c\u4e3a\u548c\u5b66\u4e60\u969c\u788d\u7b49\u795e\u7ecf\u7cbe\u795e\u75be\u75c5\u7684\u98ce\u9669\u8f83\u9ad8\u300222q11.2\u7f3a\u5931\u7efc\u5408\u5f81\u662f\u7cbe\u795e\u5206\u88c2\u75c7\u548c\u5176\u4ed6\u7cbe\u795e\u75c5\u6027\u969c\u788d\u6700\u5f3a\u7684\u5355\u4e00\u9057\u4f20\u98ce\u9669\u56e0\u7d20\uff0c\u56e0\u6b64\u8fd9\u9879\u7814\u7a76\u663e\u5f97\u5c24\u4e3a\u7d27\u8feb\u3002<\/p>\n

\u4e00\u9879\u524d\u666f\u5e7f\u9614\u7684\u7814\u7a76\u9886\u57df\u662f\u7531\u65af\u5766\u798f\u5927\u5b66\u533b\u5b66\u9662\u513f\u79d1\u65b0\u751f\u513f\u548c\u53d1\u80b2\u533b\u5b66\u52a9\u7406\u6559\u6388\u5b89\u5361\u00b7\u5e15\u65af\u5361\uff08Anca Pasca\uff09\u535a\u58eb\u9886\u5bfc\u7684\u4e00\u9879\u7814\u7a76\u3002\u5e15\u65af\u5361\u548c\u5979\u7684\u7814\u7a76\u56e2\u961f\u6b63\u5728\u5206\u6790\u643a\u5e2622q11.2\u7f3a\u5931\u7684\u53d1\u80b2\u4e2d\u8111\u7ec6\u80de\u3002\u201c\u6211\u4eec\u5173\u6ce8\u7684\u662f\u5927\u8111\u53d1\u80b2\u65e9\u671f\u7ebf\u7c92\u4f53\u7684\u529f\u80fd\u548c\u6570\u91cf\uff0c\u201d\u5e15\u65af\u5361\u8bf4\uff0c\u201c\u6211\u4eec\u60f3\u5f04\u6e05\u695a\u7ebf\u7c92\u4f53\u7684\u529f\u80fd\u662f\u5426\u53d7\u5230\u5f71\u54cd\uff0c\u5982\u4f55\u53d7\u5230\u5f71\u54cd\uff0c\u4ee5\u53ca\u5728\u5927\u8111\u53d1\u80b2\u7684\u54ea\u4e2a\u9636\u6bb5\u53d7\u5230\u5f71\u54cd\u3002\u201d<\/p>\n

\u8fc4\u4eca\u4e3a\u6b62\uff0c\u4ed6\u4eec\u7684\u7814\u7a76\u5df2\u53d1\u73b0\u8bc1\u636e\u8868\u660e\uff0c\u65e9\u5728\u598a\u5a20\u65e9\u671f\uff08\u5b55\u65e9\u671f\uff09\uff0c\u795e\u7ecf\u5143\u548c\u7ebf\u7c92\u4f53\u529f\u80fd\u5c31\u4f1a\u53d7\u5230\u5f71\u54cd\u3002\u201c\u6211\u4eec\u7684\u76ee\u6807\u662f\u627e\u5230\u4e00\u4e9b\u6807\u8bb0\u7269\uff0c\u4ee5\u4fbf\u5728\u598a\u5a20\u65e9\u671f\u8bc6\u522b\u51fa22q11.2\u7f3a\u5931\uff0c\u5e76\u8fdb\u884c\u5e72\u9884\uff0c\u201d\u5e15\u65af\u5361\u8bf4\u9053\u3002\u5e72\u9884\u63aa\u65bd\u53ef\u80fd\u5f88\u7b80\u5355\uff0c\u4f8b\u5982\u7ed9\u5b55\u5987\u670d\u7528\u836f\u7269\u6216\u8865\u5145\u5242\uff0c\u4ee5\u5e2e\u52a9\u9884\u9632\u5927\u8111\u53d1\u80b2\u5f02\u5e38\uff0c\u5e76\u964d\u4f4e\u65e5\u540e\u60a3\u7cbe\u795e\u75be\u75c5\u7684\u98ce\u9669\u3002<\/p>\n

\u514d\u75ab\u7cfb\u7edf\u53d7\u635f\u513f\u7ae5\u7684\u5e0c\u671b<\/h3>\n

\u6c49\u5bc6\u5c14\u987f\u548c\u5979\u7684\u5bb6\u4eba\u8fd8\u901a\u8fc7 22q11.2 \u7f3a\u5931\u7efc\u5408\u5f81\u8054\u76df\u652f\u6301\u5bf9\u60a3\u6709\u8fd9\u79cd\u75be\u75c5\u7684\u513f\u7ae5\u7684\u514d\u75ab\u529f\u80fd\u8fdb\u884c\u5f00\u521b\u6027\u7814\u7a76\u3002\u8be5\u8054\u76df\u4e8e 2016 \u5e74\u5728\u65af\u5766\u798f\u5927\u5b66\u7684\u786e\u8bca\u548c\u6cbb\u6108\u533b\u5b66\u4e2d\u5fc3\u6210\u7acb\u3002<\/p>\n

\u8fd9\u91cc\u6b63\u5728\u8fdb\u884c\u7684\u7814\u7a76\u53ef\u4ee5\u62ef\u6551\u751f\u547d\u3002\u201c\u8bb8\u591a\u60a3\u8005\u7684\u514d\u75ab\u7cfb\u7edf\u53d7\u635f\uff0c\u662f\u56e0\u4e3a\u80f8\u817a\u53d1\u80b2\u4e0d\u5168\uff0c\u201d\u533b\u5b66\u9662\u513f\u79d1\u5e72\u7ec6\u80de\u79fb\u690d\u548c\u518d\u751f\u533b\u5b66\u52a9\u7406\u6559\u6388\u3001\u8be5\u8054\u76df\u9879\u76ee\u8d1f\u8d23\u4eba Katja Weinacht \u533b\u5b66\u535a\u58eb\u3001\u54f2\u5b66\u535a\u58eb\u8bf4\u9053\u3002<\/p>\n

\u201c22q11.2\u7f3a\u5931\u7efc\u5408\u5f81\u7684\u514d\u75ab\u7f3a\u9677\u8868\u73b0\u591a\u79cd\u591a\u6837\uff0c\u4ece\u8f7b\u5fae\u7684\u8fc7\u654f\u5230\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\uff0c\u518d\u5230\u514d\u75ab\u7cfb\u7edf\u5b8c\u5168\u5d29\u6e83\uff0c\u4e0d\u4e00\u800c\u8db3\uff0c\u201d\u97e6\u7eb3\u8d6b\u7279\u8bf4\u3002\u201c\u5728\u60a3\u6709\u6700\u4e25\u91cd22q11.2\u7f3a\u5931\u7efc\u5408\u5f81\u7684\u513f\u7ae5\u4e2d\uff0c\u67091%\u52302%\u7684\u4eba\u5929\u751f\u6ca1\u6709\u80f8\u817a\uff0c\u201d\u80f8\u817a\u662f\u514d\u75ab\u7cfb\u7edf\u4e2d\u8d77\u7740\u81f3\u5173\u91cd\u8981\u4f5c\u7528\u7684\u5c0f\u817a\u4f53\u3002\u8fd9\u4e9b\u5b69\u5b50\u5b8c\u5168\u6ca1\u6709\u514d\u75ab\u7cfb\u7edf\uff0c\u56e0\u6b64\u5b8c\u5168\u65e0\u6cd5\u62b5\u6297\u611f\u67d3\u3002<\/p>\n

\u9b4f\u7eb3\u8d6b\u7279\u7684\u5b9e\u9a8c\u5ba4\u6b63\u5728\u8ffd\u6c42\u4e00\u4e2a\u5927\u80c6\u7684\u76ee\u6807\u2014\u2014\u8ba9\u8fd9\u4e9b\u5b69\u5b50\u62e5\u6709\u529f\u80fd\u6b63\u5e38\u7684\u80f8\u817a\u548c\u5065\u5eb7\u7684\u514d\u75ab\u7cfb\u7edf\u3002\u5979\u7684\u56e2\u961f\u6b63\u81f4\u529b\u4e8e\u5229\u7528\u6765\u81ea22q11.2\u7f3a\u5931\u7efc\u5408\u5f81\u60a3\u8005\u7684\u8bf1\u5bfc\u591a\u80fd\u5e72\u7ec6\u80de\u6765\u91cd\u5efa\u80f8\u817a\u4e0a\u76ae\u7ec6\u80de\u3002\u8be5\u56e2\u961f\u5728\u5f00\u53d1\u4e00\u79cd\u6f5c\u5728\u7684\u65b0\u7597\u6cd5\u65b9\u9762\u53d6\u5f97\u4e86\u4ee4\u4eba\u9f13\u821e\u7684\u8fdb\u5c55\u2014\u2014\u5c06\u8fd9\u4e9b\u5408\u6210\u7684\u3001\u529f\u80fd\u9f50\u5168\u7684\u518d\u751f\u80f8\u817a\u7ec4\u7ec7\u79fb\u690d\u56de\u60a3\u8005\u4f53\u5185\uff0c\u4ee5\u91cd\u5efa\u80fd\u591f\u4ea7\u751f\u5bf9\u6297\u611f\u67d3\u6240\u9700T\u7ec6\u80de\u7684\u80f8\u817a\u3002<\/p>\n

\u771f\u6b63\u80fd\u6301\u7eed\u5e26\u6765\u60ca\u559c\u7684\u793c\u7269<\/h3>\n

\u201c\u5bf9\u4e8e\u60a3\u8005\u53ca\u5176\u5bb6\u4eba\u6765\u8bf4\uff0c\u542c\u523022q11.2\u7f3a\u5931\u7efc\u5408\u5f81\u7684\u8bca\u65ad\u7ed3\u679c\u4f1a\u5f7b\u5e95\u6539\u53d8\u4ed6\u4eec\u7684\u751f\u6d3b\uff0c\u201d\u5e15\u65af\u5361\u8bf4\u3002\u201c\u6211\u5e0c\u671b\u6211\u4eec\u80fd\u591f\u4e3a\u4e00\u9879\u7a81\u7834\u6027\u8fdb\u5c55\u505a\u51fa\u8d21\u732e\uff0c\u8fd9\u9879\u7a81\u7834\u5c06\u4e3a\u4e34\u5e8a\u8bd5\u9a8c\u63d0\u4f9b\u4fe1\u606f\uff0c\u5e76\u5927\u5927\u52a0\u5feb\u8fd9\u4e00\u9886\u57df\u7684\u7814\u7a76\u8fdb\u7a0b\u3002\u201d<\/p>\n

\u5982\u679c\u6ca1\u6709\u6148\u5584\u6350\u52a9\uff0c\u79d1\u7814\u7a81\u7834\u53ca\u5176\u53d1\u751f\u7684\u901f\u5ea6\u662f\u4e0d\u53ef\u80fd\u5b9e\u73b0\u7684\u3002\u201c\u6350\u52a9\u8005\u7684\u652f\u6301\u51b3\u5b9a\u4e86\u8fd9\u9879\u7814\u7a76\u662f\u9700\u8981\u8017\u8d39\u591a\u5e74\u65f6\u95f4\uff0c\u8fd8\u662f\u80fd\u591f\u5feb\u901f\u63a8\u8fdb\u5e76\u5c3d\u5feb\u627e\u5230\u7b54\u6848\uff0c\u201d\u5e15\u65af\u5361\u8bf4\u9053\u3002<\/p>\n

\u6350\u52a9\u8005\u7684\u652f\u6301\u4f7f\u65af\u5766\u798f\u5927\u5b66\u5728\u7f8e\u56fd\u4e43\u81f3\u56fd\u9645\u4e0a22q11.2\u7f3a\u5931\u7efc\u5408\u5f81\u7684\u7814\u7a76\u9886\u57df\u5904\u4e8e\u9886\u5148\u5730\u4f4d\u3002\u201c\u7531\u4e8e\u6211\u4eec\u83b7\u5f97\u4e86\u8fd9\u7b14\u8d44\u91d1\uff0c\u51e0\u4e2a\u5b9e\u9a8c\u5ba4\u5f00\u59cb\u5408\u4f5c\uff0c\u5171\u4eab\u5de5\u5177\u548c\u7814\u7a76\u6210\u679c\uff0c\u5171\u540c\u62fc\u51d1\u51fa\u95ee\u9898\u7684\u7b54\u6848\uff0c\u201d\u97e6\u7eb3\u8d6b\u7279\u8bf4\u3002\u201c\u611f\u8c22\u4e4c\u4f0a\u6ed5\u82cf-\u6c49\u5bc6\u5c14\u987f\u5bb6\u65cf\u7684\u6177\u6168\u652f\u6301\uff0c\u65af\u5766\u798f\u5927\u5b66\u53ca\u5176\u4ed6\u673a\u6784\u7684\u8de8\u5b66\u79d122q11\u7814\u7a76\u84ec\u52c3\u53d1\u5c55\uff0c\u4e3a\u9700\u8981\u5e2e\u52a9\u7684\u513f\u7ae5\u548c\u5bb6\u5ead\u5e26\u6765\u4e86\u65b0\u7684\u5e0c\u671b\u3002\u201d<\/p>\n

 <\/p>\n

\u8981\u4e86\u89e3\u66f4\u591a\u5173\u4e8e 22q11.2 \u7f3a\u5931\u7efc\u5408\u5f81\u7684\u4fe1\u606f\uff0c\u8bf7\u9605\u8bfb \u533b\u5b66\u535a\u58eb\u585e\u5c14\u5409\u4e4c\u00b7\u5e15\u65af\u5361\u6b63\u5728\u9769\u65b0\u795e\u7ecf\u7cfb\u7edf\u75be\u75c5\u7684\u7814\u7a76\u3002<\/em><\/a>.<\/p>","protected":false},"excerpt":{"rendered":"

\u9664\u975e\u60a8\u7684\u5bb6\u65cf\u60a3\u670922q11.2\u7f3a\u5931\u7efc\u5408\u5f81\uff0822q11.2DS\uff09\uff0c\u5426\u5219\u60a8\u53ef\u80fd\u4ece\u672a\u542c\u8bf4\u8fc7\u8fd9\u79cd\u75be\u75c5\u3002\u636e\u4f30\u8ba1\uff0c\u6bcf2000\u52304000\u4eba\u4e2d\u5c31\u6709\u4e00\u4eba\u60a3\u6709\u6b64\u75c5\u2026\u2026<\/p>","protected":false},"author":17,"featured_media":15262,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"categories":[164],"class_list":["post-4307","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-research","health_topic-medical-complexity"],"acf":[],"yoast_head":"\nUnraveling the Mysteries of 22q11.2 Deletion Syndrome - Lucile Packard Foundation for Children's Health<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"http:\/\/lpfch.org\/zh\/impact-stories\/unraveling-the-mysteries-of-22q11-2-deletion-syndrome\/\" \/>\n<meta property=\"og:locale\" content=\"zh_CN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Unraveling the Mysteries of 22q11.2 Deletion Syndrome\" \/>\n<meta property=\"og:description\" content=\"Unless your family is affected by 22q11.2 deletion syndrome (22q11.2DS), you may have never heard of it. It\u2019s estimated that one in 2,000 to 4,000...\" \/>\n<meta property=\"og:url\" content=\"http:\/\/lpfch.org\/zh\/impact-stories\/unraveling-the-mysteries-of-22q11-2-deletion-syndrome\/\" \/>\n<meta property=\"og:site_name\" content=\"Lucile Packard Foundation for Children's Health\" \/>\n<meta property=\"article:published_time\" content=\"2022-11-09T01:01:43+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-11-22T20:21:29+00:00\" \/>\n<meta property=\"og:image\" content=\"http:\/\/lpfch.org\/wp-content\/uploads\/2024\/02\/blog_img_1_4_0-scaled.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"2560\" \/>\n\t<meta property=\"og:image:height\" content=\"1417\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"admin\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"admin\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"5 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"http:\\\/\\\/lpfch.org\\\/ja\\\/impact-stories\\\/unraveling-the-mysteries-of-22q11-2-deletion-syndrome\\\/#article\",\"isPartOf\":{\"@id\":\"http:\\\/\\\/lpfch.org\\\/ja\\\/impact-stories\\\/unraveling-the-mysteries-of-22q11-2-deletion-syndrome\\\/\"},\"author\":{\"name\":\"admin\",\"@id\":\"https:\\\/\\\/lpfch.org\\\/#\\\/schema\\\/person\\\/0c27ee3a03f60d4845413e6163db996c\"},\"headline\":\"Unraveling the Mysteries of 22q11.2 Deletion Syndrome\",\"datePublished\":\"2022-11-09T01:01:43+00:00\",\"dateModified\":\"2024-11-22T20:21:29+00:00\",\"mainEntityOfPage\":{\"@id\":\"http:\\\/\\\/lpfch.org\\\/ja\\\/impact-stories\\\/unraveling-the-mysteries-of-22q11-2-deletion-syndrome\\\/\"},\"wordCount\":935,\"commentCount\":0,\"image\":{\"@id\":\"http:\\\/\\\/lpfch.org\\\/ja\\\/impact-stories\\\/unraveling-the-mysteries-of-22q11-2-deletion-syndrome\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/lpfch.org\\\/wp-content\\\/uploads\\\/2024\\\/02\\\/blog_img_1_4_0-scaled.jpg\",\"articleSection\":[\"Research\"],\"inLanguage\":\"zh-CN\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"http:\\\/\\\/lpfch.org\\\/ja\\\/impact-stories\\\/unraveling-the-mysteries-of-22q11-2-deletion-syndrome\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"http:\\\/\\\/lpfch.org\\\/ja\\\/impact-stories\\\/unraveling-the-mysteries-of-22q11-2-deletion-syndrome\\\/\",\"url\":\"http:\\\/\\\/lpfch.org\\\/ja\\\/impact-stories\\\/unraveling-the-mysteries-of-22q11-2-deletion-syndrome\\\/\",\"name\":\"Unraveling the Mysteries of 22q11.2 Deletion Syndrome - Lucile Packard Foundation for Children's Health\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/lpfch.org\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"http:\\\/\\\/lpfch.org\\\/ja\\\/impact-stories\\\/unraveling-the-mysteries-of-22q11-2-deletion-syndrome\\\/#primaryimage\"},\"image\":{\"@id\":\"http:\\\/\\\/lpfch.org\\\/ja\\\/impact-stories\\\/unraveling-the-mysteries-of-22q11-2-deletion-syndrome\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/lpfch.org\\\/wp-content\\\/uploads\\\/2024\\\/02\\\/blog_img_1_4_0-scaled.jpg\",\"datePublished\":\"2022-11-09T01:01:43+00:00\",\"dateModified\":\"2024-11-22T20:21:29+00:00\",\"author\":{\"@id\":\"https:\\\/\\\/lpfch.org\\\/#\\\/schema\\\/person\\\/0c27ee3a03f60d4845413e6163db996c\"},\"breadcrumb\":{\"@id\":\"http:\\\/\\\/lpfch.org\\\/ja\\\/impact-stories\\\/unraveling-the-mysteries-of-22q11-2-deletion-syndrome\\\/#breadcrumb\"},\"inLanguage\":\"zh-CN\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"http:\\\/\\\/lpfch.org\\\/ja\\\/impact-stories\\\/unraveling-the-mysteries-of-22q11-2-deletion-syndrome\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"zh-CN\",\"@id\":\"http:\\\/\\\/lpfch.org\\\/ja\\\/impact-stories\\\/unraveling-the-mysteries-of-22q11-2-deletion-syndrome\\\/#primaryimage\",\"url\":\"https:\\\/\\\/lpfch.org\\\/wp-content\\\/uploads\\\/2024\\\/02\\\/blog_img_1_4_0-scaled.jpg\",\"contentUrl\":\"https:\\\/\\\/lpfch.org\\\/wp-content\\\/uploads\\\/2024\\\/02\\\/blog_img_1_4_0-scaled.jpg\",\"width\":2560,\"height\":1417},{\"@type\":\"BreadcrumbList\",\"@id\":\"http:\\\/\\\/lpfch.org\\\/ja\\\/impact-stories\\\/unraveling-the-mysteries-of-22q11-2-deletion-syndrome\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/lpfch.org\\\/zh\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Unraveling the Mysteries…\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/lpfch.org\\\/#website\",\"url\":\"https:\\\/\\\/lpfch.org\\\/\",\"name\":\"Lucile Packard Foundation for Children's Health\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/lpfch.org\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"zh-CN\"},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/lpfch.org\\\/#\\\/schema\\\/person\\\/0c27ee3a03f60d4845413e6163db996c\",\"name\":\"admin\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"zh-CN\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/01a869e9508babcb1c66b6b41356b4ef63d5326e5b27c38b27ed4a46b8e36b9f?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/01a869e9508babcb1c66b6b41356b4ef63d5326e5b27c38b27ed4a46b8e36b9f?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/01a869e9508babcb1c66b6b41356b4ef63d5326e5b27c38b27ed4a46b8e36b9f?s=96&d=mm&r=g\",\"caption\":\"admin\"},\"sameAs\":[\"https:\\\/\\\/lpfch.org\\\/wp\"],\"url\":\"https:\\\/\\\/lpfch.org\\\/zh\\\/impact-stories\\\/author\\\/admin\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Unraveling the Mysteries of 22q11.2 Deletion Syndrome - Lucile Packard Foundation for Children's Health","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"http:\/\/lpfch.org\/zh\/impact-stories\/unraveling-the-mysteries-of-22q11-2-deletion-syndrome\/","og_locale":"zh_CN","og_type":"article","og_title":"Unraveling the Mysteries of 22q11.2 Deletion Syndrome","og_description":"Unless your family is affected by 22q11.2 deletion syndrome (22q11.2DS), you may have never heard of it. It\u2019s estimated that one in 2,000 to 4,000...","og_url":"http:\/\/lpfch.org\/zh\/impact-stories\/unraveling-the-mysteries-of-22q11-2-deletion-syndrome\/","og_site_name":"Lucile Packard Foundation for Children's Health","article_published_time":"2022-11-09T01:01:43+00:00","article_modified_time":"2024-11-22T20:21:29+00:00","og_image":[{"width":2560,"height":1417,"url":"http:\/\/lpfch.org\/wp-content\/uploads\/2024\/02\/blog_img_1_4_0-scaled.jpg","type":"image\/jpeg"}],"author":"admin","twitter_card":"summary_large_image","twitter_misc":{"Written by":"admin","Est. reading time":"5 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"http:\/\/lpfch.org\/ja\/impact-stories\/unraveling-the-mysteries-of-22q11-2-deletion-syndrome\/#article","isPartOf":{"@id":"http:\/\/lpfch.org\/ja\/impact-stories\/unraveling-the-mysteries-of-22q11-2-deletion-syndrome\/"},"author":{"name":"admin","@id":"https:\/\/lpfch.org\/#\/schema\/person\/0c27ee3a03f60d4845413e6163db996c"},"headline":"Unraveling the Mysteries of 22q11.2 Deletion Syndrome","datePublished":"2022-11-09T01:01:43+00:00","dateModified":"2024-11-22T20:21:29+00:00","mainEntityOfPage":{"@id":"http:\/\/lpfch.org\/ja\/impact-stories\/unraveling-the-mysteries-of-22q11-2-deletion-syndrome\/"},"wordCount":935,"commentCount":0,"image":{"@id":"http:\/\/lpfch.org\/ja\/impact-stories\/unraveling-the-mysteries-of-22q11-2-deletion-syndrome\/#primaryimage"},"thumbnailUrl":"https:\/\/lpfch.org\/wp-content\/uploads\/2024\/02\/blog_img_1_4_0-scaled.jpg","articleSection":["Research"],"inLanguage":"zh-CN","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["http:\/\/lpfch.org\/ja\/impact-stories\/unraveling-the-mysteries-of-22q11-2-deletion-syndrome\/#respond"]}]},{"@type":"WebPage","@id":"http:\/\/lpfch.org\/ja\/impact-stories\/unraveling-the-mysteries-of-22q11-2-deletion-syndrome\/","url":"http:\/\/lpfch.org\/ja\/impact-stories\/unraveling-the-mysteries-of-22q11-2-deletion-syndrome\/","name":"Unraveling the Mysteries of 22q11.2 Deletion Syndrome - Lucile Packard Foundation for Children's Health","isPartOf":{"@id":"https:\/\/lpfch.org\/#website"},"primaryImageOfPage":{"@id":"http:\/\/lpfch.org\/ja\/impact-stories\/unraveling-the-mysteries-of-22q11-2-deletion-syndrome\/#primaryimage"},"image":{"@id":"http:\/\/lpfch.org\/ja\/impact-stories\/unraveling-the-mysteries-of-22q11-2-deletion-syndrome\/#primaryimage"},"thumbnailUrl":"https:\/\/lpfch.org\/wp-content\/uploads\/2024\/02\/blog_img_1_4_0-scaled.jpg","datePublished":"2022-11-09T01:01:43+00:00","dateModified":"2024-11-22T20:21:29+00:00","author":{"@id":"https:\/\/lpfch.org\/#\/schema\/person\/0c27ee3a03f60d4845413e6163db996c"},"breadcrumb":{"@id":"http:\/\/lpfch.org\/ja\/impact-stories\/unraveling-the-mysteries-of-22q11-2-deletion-syndrome\/#breadcrumb"},"inLanguage":"zh-CN","potentialAction":[{"@type":"ReadAction","target":["http:\/\/lpfch.org\/ja\/impact-stories\/unraveling-the-mysteries-of-22q11-2-deletion-syndrome\/"]}]},{"@type":"ImageObject","inLanguage":"zh-CN","@id":"http:\/\/lpfch.org\/ja\/impact-stories\/unraveling-the-mysteries-of-22q11-2-deletion-syndrome\/#primaryimage","url":"https:\/\/lpfch.org\/wp-content\/uploads\/2024\/02\/blog_img_1_4_0-scaled.jpg","contentUrl":"https:\/\/lpfch.org\/wp-content\/uploads\/2024\/02\/blog_img_1_4_0-scaled.jpg","width":2560,"height":1417},{"@type":"BreadcrumbList","@id":"http:\/\/lpfch.org\/ja\/impact-stories\/unraveling-the-mysteries-of-22q11-2-deletion-syndrome\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/lpfch.org\/zh\/"},{"@type":"ListItem","position":2,"name":"Unraveling the Mysteries…"}]},{"@type":"WebSite","@id":"https:\/\/lpfch.org\/#website","url":"https:\/\/lpfch.org\/","name":"\u9732\u897f\u5c14\u00b7\u5e15\u5361\u5fb7\u513f\u7ae5\u5065\u5eb7\u57fa\u91d1\u4f1a","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/lpfch.org\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"zh-CN"},{"@type":"Person","@id":"https:\/\/lpfch.org\/#\/schema\/person\/0c27ee3a03f60d4845413e6163db996c","name":"\u884c\u653f","image":{"@type":"ImageObject","inLanguage":"zh-CN","@id":"https:\/\/secure.gravatar.com\/avatar\/01a869e9508babcb1c66b6b41356b4ef63d5326e5b27c38b27ed4a46b8e36b9f?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/01a869e9508babcb1c66b6b41356b4ef63d5326e5b27c38b27ed4a46b8e36b9f?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/01a869e9508babcb1c66b6b41356b4ef63d5326e5b27c38b27ed4a46b8e36b9f?s=96&d=mm&r=g","caption":"admin"},"sameAs":["https:\/\/lpfch.org\/wp"],"url":"https:\/\/lpfch.org\/zh\/impact-stories\/author\/admin\/"}]}},"_links":{"self":[{"href":"https:\/\/lpfch.org\/zh\/wp-json\/wp\/v2\/posts\/4307","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lpfch.org\/zh\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lpfch.org\/zh\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lpfch.org\/zh\/wp-json\/wp\/v2\/users\/17"}],"replies":[{"embeddable":true,"href":"https:\/\/lpfch.org\/zh\/wp-json\/wp\/v2\/comments?post=4307"}],"version-history":[{"count":3,"href":"https:\/\/lpfch.org\/zh\/wp-json\/wp\/v2\/posts\/4307\/revisions"}],"predecessor-version":[{"id":19478,"href":"https:\/\/lpfch.org\/zh\/wp-json\/wp\/v2\/posts\/4307\/revisions\/19478"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/lpfch.org\/zh\/wp-json\/wp\/v2\/media\/15262"}],"wp:attachment":[{"href":"https:\/\/lpfch.org\/zh\/wp-json\/wp\/v2\/media?parent=4307"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lpfch.org\/zh\/wp-json\/wp\/v2\/categories?post=4307"}],"curies":[{"name":"\u53ef\u6e7f\u6027\u7c89\u5242","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}